Please use this identifier to cite or link to this item:
http://repositorio.unicamp.br/jspui/handle/REPOSIP/352741
Type: | Artigo |
Title: | Optimised NLC: a nanotechnological approach to improve the anaesthetic effect of bupivacaine |
Author: | Rodrigues da Silva, Gustavo H. Ribeiro, Lígia N.M. Mitsutake, Hery Guilherme, Viviane A. Castro, Simone R. Poppi, Ronei J. Breitkreitz, Márcia C. Paula, Eneida de |
Abstract: | The short time of action and systemic toxicity of local anaesthetics limit their clinical application. Bupivacaine is the most frequently used local anaesthetic in surgical procedures worldwide. The discovery that its S(−) enantiomeric form is less toxic |
Subject: | Bupivacaína Planejamento fatorial Carregadores lipídicos nanoestruturados Anestésicos locais Bupivacaine Factorial experiment designs Nanostructured lipidic carriers Local anesthetics |
Country: | Países Baixos |
Editor: | Elsevier |
Rights: | Fechado |
Identifier DOI: | 10.1016/j.ijpharm.2017.06.066 |
Address: | https://www.sciencedirect.com/science/article/pii/S0378517317305744 |
Date Issue: | 2017 |
Appears in Collections: | IQ - Artigos e Outros Documentos IB - Artigos e Outros Documentos |
Files in This Item:
File | Size | Format | |
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2-s2.0-85022100470.pdf | 4.31 MB | Adobe PDF | View/Open |
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