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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampMarques, Marcelo Rocha-
dc.typeArtigopt_BR
dc.titleEffects of Cachaca, a typical Brazilian alcoholic beverage, on alveolar bone loss and density: a study in peripubertal ratspt_BR
dc.contributor.authorBastos, M. F.-
dc.contributor.authorGabrili, J. J. M.-
dc.contributor.authorRomero, J. R.-
dc.contributor.authorDuarte, P. M.-
dc.contributor.authorGaag, G. L. D.-
dc.contributor.authorMarques, M. R.-
dc.subjectPerda do osso alveolarpt_BR
dc.subjectFosfatase ácidapt_BR
dc.subject.otherlanguageAlveolar bone losspt_BR
dc.subject.otherlanguageAcid phosphatasept_BR
dc.description.abstractThe aim of the present study was to assess the impact of chronic consumption of Cachaca on alveolar bone loss (BL) induced by ligature and on alveolar bone density (BD) in peripubertal rats. Male Wistar rats were assigned into one of the following groups: Control: non-ingestion of Cachaca (n = 15); Cachaca: ingestion of ascending concentrations of Cachaca during 100 days (n = 15). 70th day after the beginning of Cachaca ingestion, one first mandibular molar received a ligature while the contralateral tooth was left unligated. After 30 days, the rats were killed. BL, BD, the positive cells for tartrate-resistant acid phosphatase (TRAP), receptor activator of NF-kappa B ligand (RANKL) and osteoprotegerin (OPG) were analyzed in the furcation area of the ligated and unligated mandibular molars. The Cachaca group presented greater BL (0.75 +/- 0.1 mm(2) for Cachaca and 0.66 +/- 0.1 mm(2) for control group, respectively) and number of RANKL and OPG+ cells and lower BD (60.3 +/- 4.2% for Cachaca and 76.8 +/- 3.8% for control group, respectively) and number of TRAP+ cells around ligated teeth (p < 0.05), when compared to the control group. The Cachaca group (0.42 +/- 0.02 mm(2)) also presented a higher BL around unligated teeth when compared to control group (0.31 +/- 0.05 mm(2)). Cachaca consumption per se and in the presence of ligature negatively affects alveolar bone by increasing the alveolar BL and reducing BDpt_BR
dc.relation.ispartofArchives of oral biologypt_BR
dc.relation.ispartofabbreviationArch. oral biol.pt_BR
dc.publisher.cityOxfordpt_BR
dc.publisher.countryReino Unidopt_BR
dc.publisherElsevierpt_BR
dc.date.issued2014-
dc.date.monthofcirculationJan.pt_BR
dc.language.isoengpt_BR
dc.description.volume59pt_BR
dc.description.issuenumber1pt_BR
dc.description.firstpage82pt_BR
dc.description.lastpage91pt_BR
dc.rightsFechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn0003-9969pt_BR
dc.identifier.eissn1879-1506pt_BR
dc.identifier.doi10.1016/j.archoralbio.2013.10.002pt_BR
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0003996913003130pt_BR
dc.description.sponsorshipFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPpt_BR
dc.description.sponsordocumentnumber2009/09446-6pt_BR
dc.date.available2020-11-09T17:01:08Z-
dc.date.accessioned2020-11-09T17:01:08Z-
dc.description.provenanceSubmitted by Cintia Oliveira de Moura (cintiaom@unicamp.br) on 2020-11-09T17:01:08Z No. of bitstreams: 0. Added 1 bitstream(s) on 2021-02-16T16:52:53Z : No. of bitstreams: 1 000328432300010.pdf: 2825326 bytes, checksum: 67d8fef3b6b5637c196a0e0b3e8261e7 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-11-09T17:01:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2014en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/352031-
dc.contributor.departmentDepartamento de Morfologiapt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.subject.keywordRANK ligandpt_BR
dc.subject.keywordOsteoprotegerinpt_BR
dc.identifier.source000328432300010pt_BR
dc.creator.orcid0000-0001-9771-9844pt_BR
dc.type.formArtigopt_BR
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