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Type: Artigo
Title: Effects of Cachaca, a typical Brazilian alcoholic beverage, on alveolar bone loss and density: a study in peripubertal rats
Author: Bastos, M. F.
Gabrili, J. J. M.
Romero, J. R.
Duarte, P. M.
Gaag, G. L. D.
Marques, M. R.
Abstract: The aim of the present study was to assess the impact of chronic consumption of Cachaca on alveolar bone loss (BL) induced by ligature and on alveolar bone density (BD) in peripubertal rats. Male Wistar rats were assigned into one of the following groups: Control: non-ingestion of Cachaca (n = 15); Cachaca: ingestion of ascending concentrations of Cachaca during 100 days (n = 15). 70th day after the beginning of Cachaca ingestion, one first mandibular molar received a ligature while the contralateral tooth was left unligated. After 30 days, the rats were killed. BL, BD, the positive cells for tartrate-resistant acid phosphatase (TRAP), receptor activator of NF-kappa B ligand (RANKL) and osteoprotegerin (OPG) were analyzed in the furcation area of the ligated and unligated mandibular molars. The Cachaca group presented greater BL (0.75 +/- 0.1 mm(2) for Cachaca and 0.66 +/- 0.1 mm(2) for control group, respectively) and number of RANKL and OPG+ cells and lower BD (60.3 +/- 4.2% for Cachaca and 76.8 +/- 3.8% for control group, respectively) and number of TRAP+ cells around ligated teeth (p < 0.05), when compared to the control group. The Cachaca group (0.42 +/- 0.02 mm(2)) also presented a higher BL around unligated teeth when compared to control group (0.31 +/- 0.05 mm(2)). Cachaca consumption per se and in the presence of ligature negatively affects alveolar bone by increasing the alveolar BL and reducing BD
Subject: Perda do osso alveolar
Fosfatase ácida
Country: Reino Unido
Editor: Elsevier
Rights: Fechado
Identifier DOI: 10.1016/j.archoralbio.2013.10.002
Date Issue: 2014
Appears in Collections:FOP - Artigos e Outros Documentos

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