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Type: Artigo
Title: Comparative study of chemical composition and biological activity of yellow, green, brown, and red brazilian propolis
Author: Machado, Christiane Schineider
Mokochinski, João Benhur
Lira, Tatiana Onofre de
de Oliveira, Fátima de Cassia Evangelista
Cardoso, Magda Vieira
Ferreira, Roseane Guimarães
Frankland Sawaya, Alexandra Christine Helena
Ferreira, Antonio Gilberto
Pessoa, Cláudia
Cuesta-Rubio, Osmany
Monteiro, Marta Chagas
de Campos, Mônica Soares
Torres, Yohandra Reyes
Abstract: The chemical composition and biological activity of a sample of yellow propolis from Mato Grosso do Sul, Brazil (EEP-Y MS), were investigated for the first time and compared with green, brown, and red types of Brazilian propolis and with a sample of yellow propolis from Cuba. Overall, EEP-Y MS had different qualitative chemical profiles, as well as different cytotoxic and antimicrobial activities when compared to the other types of propolis assessed in this study and it is a different chemotype of Brazilian propolis. Absence of phenolic compounds and the presence of mixtures of aliphatic compounds in yellow propolis were determined by analysing H-1-NMR spectra and fifteen terpenes were identified by GC-MS. EEP-Y MS showed cytotoxic activity against human tumour strain OVCAR-8 but was not active against Gram-negative or Gram-positive bacteria. Our results confirm the difficulty of establishing a uniform quality standard for propolis from diverse geographical origins. The most appropriate pharmacological applications of yellow types of propolis must be further investigated
Subject: Própolis
Country: Reino Unido
Editor: Hindawi
Rights: Aberto
Identifier DOI: 10.1155/2016/6057650
Date Issue: 2016
Appears in Collections:IB - Artigos e Outros Documentos
FCF - Artigos e Outros Documentos

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