Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/350597
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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampAlves de Ávila, Amanda Rejane-
dc.contributor.authorunicampQueirós, Lívia Dias de-
dc.contributor.authorunicampLopes, Danielle Branta-
dc.contributor.authorunicampBarin, Clara Guido-
dc.contributor.authorunicampUeta, Tatiane Mayumi-
dc.contributor.authorunicampRuiz, Ana Lucia Tasca Gois-
dc.contributor.authorunicampMacedo, Gabriela Alves-
dc.contributor.authorunicampMacedo, Juliana Alves-
dc.typeArtigopt_BR
dc.titleEnhanced estrogenic effects of biotransformed soy extractspt_BR
dc.contributor.authorÁvila, Amanda Rejane Alves de-
dc.contributor.authorQueirós, Lívia Dias de-
dc.contributor.authorLopes, Danielle Branta-
dc.contributor.authorBarin, Clara Guido-
dc.contributor.authorUeta, Tatiane Mayumi-
dc.contributor.authorRuiz, Ana Lúcia Tasca Gois-
dc.contributor.authorMacedo, Gabriela Alves-
dc.contributor.authorMacedo, Juliana Alves-
dc.subjectBioatividadept_BR
dc.subject.otherlanguageBioactivitypt_BR
dc.description.abstractSoy isoflavones have been associated with several beneficial effects to human health including estrogenic action. Due to the risks associated with pharmaceutical hormone replacement therapy, soy extracts rich in isoflavones and metabolites appear as a safe alternative for menopausal women. This study aimed to improve the process conditions for biotransformation of soymilk polyphenols by tannase to obtain higher amounts of isoflavone aglycones and metabolites such as equol. The estrogenic potential of the extracts was evaluated in in vitro assays. The results showed that the aglycones increased 36–46 times after reaction with tannase and proved that it is possible to produce equol in soymilk using an enzymatic bioprocess, without gut microbial intervention. Moreover, the soymilk biotransformed by tannase presented higher estrogenic action in the MCF-7 BUS cell line assay, making it a promising nutraceutical with possible effects in the attenuation or treatment of menopause symptomspt_BR
dc.relation.ispartofJournal of functional foodspt_BR
dc.relation.ispartofabbreviationJ. funct. foods.pt_BR
dc.publisher.cityAmsterdampt_BR
dc.publisher.countryPaíses Baixospt_BR
dc.publisherElsevierpt_BR
dc.date.issued2018-
dc.date.monthofcirculationSept.pt_BR
dc.language.isoengpt_BR
dc.description.volume48pt_BR
dc.description.firstpage117pt_BR
dc.description.lastpage124pt_BR
dc.rightsFechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn1756-4646pt_BR
dc.identifier.eissn2214-9414pt_BR
dc.identifier.doi10.1016/j.jff.2018.06.026pt_BR
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S1756464618303220pt_BR
dc.description.sponsorshipCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESpt_BR
dc.description.sponsorshipFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPpt_BR
dc.description.sponsordocumentnumberSem informaçãopt_BR
dc.description.sponsordocumentnumber17367-7, 2014pt_BR
dc.date.available2020-10-06T18:19:30Z-
dc.date.accessioned2020-10-06T18:19:30Z-
dc.description.provenanceSubmitted by Thais de Brito Barroso (tbrito@unicamp.br) on 2020-10-06T18:19:30Z No. of bitstreams: 0. Added 1 bitstream(s) on 2021-01-12T13:38:47Z : No. of bitstreams: 1 000447573600012.pdf: 1124938 bytes, checksum: d449b77bfad1f392f658e4093b400fba (MD5)en
dc.description.provenanceMade available in DSpace on 2020-10-06T18:19:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2018en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/350597-
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentDepartamento de Ciência de Alimentospt_BR
dc.contributor.departmentDepartamento de Alimentos e Nutriçãopt_BR
dc.contributor.unidadeFaculdade de Engenharia de Alimentospt_BR
dc.contributor.unidadeFaculdade de Ciências Farmacêuticaspt_BR
dc.subject.keywordEnzymatic biotransformationpt_BR
dc.subject.keywordEquolpt_BR
dc.subject.keywordEstrogenic potentialpt_BR
dc.subject.keywordSoy isoflavonespt_BR
dc.subject.keywordTannasept_BR
dc.identifier.source000447573600012pt_BR
dc.creator.orcid0000-0003-4466-3853pt_BR
dc.creator.orcid0000-0003-2005-456Xpt_BR
dc.creator.orcid0000-0002-5349-3588pt_BR
dc.creator.orcidSem informaçãopt_BR
dc.creator.orcidSem informaçãopt_BR
dc.creator.orcid0000-0002-0844-8702pt_BR
dc.creator.orcid0000-0001-5255-2243pt_BR
dc.creator.orcid0000-0001-7504-8111pt_BR
dc.type.formArtigopt_BR
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