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Type: Artigo
Title: PHEMA hydrogels
Author: Passos, M. F.
Dias, D. R. C.
Bastos, G. N. T.
Jardini, A. L.
Benatti, A. C. B.
Dias, C. G. B. T.
Maciel Filho, R.
Abstract: Hydrogels of poly (2-hydroxyethyl methacrylate) (pHEMA) are suitable materials for medical applications. Synthesis, structural characterization, kinetic, physical properties and cell viability of these materials are reported in this article. The system was conducted via free radical polymerization in the absence of solvents or cross-linking agents. Hydrogels were obtained with excellent dimensional stability and high thermal stability (738 K), glass transition temperature of approximately 375 K and a degree of swelling of 66 ± 4 % in ethanol. The conversion of C=C double bond of the monomer 2-hydroxyethyl methacrylate was confirmed by Fourier transform infrared spectroscopy. Results showed dense and rough morphologies in the pHEMA, presence of high molecular interactions and good resistance to various organic solvents. In vitro tests showed excellent cell viability. The materials did not display cytotoxicity, and cells proliferated and adhered at a satisfactory rate on the hydrogel. These materials have great potential for biomedical application
Subject: Hidrogéis
Country: Hungria
Editor: Springer
Rights: Fechado
Identifier DOI: 10.1007/s10973-016-5329-6
Date Issue: 2016
Appears in Collections:FEQ - Artigos e Outros Documentos

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