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Type: Artigo
Title: Cognitive disorders and antiphospholipid antibodies
Author: Yelnik, Cécile M.
Kozora, Elizabeth
Appenzeller, Simone
Abstract: Cognitive disorders have frequently been described in the field of antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE). Nevertheless, the relationship between those disorders and antiphospholipid antibodies (aPL) remains unclear and seems to involve various mechanisms. Overlap with systemic lupus erythematosus, the small sample size of studies, and discrepancies in antiphospholipid antibodies and cognitive impairment determinations complicate analyses of the literature data. In this paper, we summarize current knowledge on epidemiologic, clinical data, imaging findings and treatment of cognitive dysfunction associated with aPL. We separately analyzed data on aPL-positive carriers without history of clinical feature of APS, APS patients without overlaps autoimmune disease, and SLE-associated aPL patients
Subject: Síndrome antifosfolipídica
Country: Estados Unidos
Editor: Elsevier
Rights: Fechado
Identifier DOI: 10.1016/j.autrev.2016.09.002
Date Issue: 2016
Appears in Collections:FCM - Artigos e Outros Documentos

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