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|Title:||PLLA synthesis and membrane production through rotary jet spinning process poly (L-lactic acid) synthesis and physico-chemical analysis|
|Author:||Ciocca, Bárbara Etruri|
Miranda, Nahieh Toscano
Cardoso, Guinea Brasil Camargo
Rodrigues, Ana Amélia
Pattaro, Ana Flávia
Munhoz, André Luiz Jardini
Maciel Filho, Rubens
|Abstract:||Poly (L-lactic acid) (PLLA) is a well-established polymer, which is widely used in a wide range of fields; however, it is a high cost material, presenting great difficulties for its purchase. Therefore, the present work proposes PLLA synthesis in the laboratory, as an alternative to turn this more feasible; its processing through rotary jet spinning to obtain fibrous membranes; its physico-chemical analyses for material characterization; and, in vitro cell viability analyses with osteoblasts and fibroblasts. Scanning Electron Microscopy (SEM), Thermogravimetric Analysis (TGA), Energy Dispersive Spectroscopy (EDS), and Live/Dead® assays were the characterization analyzes of the obtained membrane. PLLA membranes had initial degradation at 200 °C, and none harmful chemical elements were present. In vitro test verified the compatibility of the membranes with two cell lines, indicating a possible and potential application of these membranes in the medical field|
|Appears in Collections:||FEQ - Artigos e Outros Documentos|
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