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Type: Artigo
Title: Bioactivity of flavonoids isolated from lychnophora markgravii against leishmania amazonensis amastigotes
Author: Salvador, Marcos José
Sartori, Fabiana Terezinha
Sacilotto, Ana Claudia B. C.
Pral, Elizabeth M. F.
Alfieri, Silvia Celina
Vichnewski, Walter
Abstract: The bioactivity of the flavonoids pinostrobin (1), pinocembrin (2), tectochrysin (3), galangin 3-methyl ether (4), and tiliroside (5) isolated from Lychnophora markgravii aerial parts was investigated in vitro against amastigote stages of Leishmania amazonensis. The compounds were isolated by several chromatographic techniques and their chemical structures were established by ESI-MS and NMR spectroscopic data. The flavonoids 1 and 3 were the most active compounds; they markedly reduced the viability of Leishmania amastigotes
Subject: Flavonóides
Atividade biológica
Country: Alemanha
Editor: Walter de Gruyter GmbH
Rights: Fechado
Identifier DOI: 10.1515/znc-2009-7-807
Date Issue: 2014
Appears in Collections:IB - Artigos e Outros Documentos

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