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Type: Artigo
Title: Lead deposition in bovine enamel during a pH-cycling regimen simulating the caries process
Author: Molina, G.F.
Costa De Almeida, G.R.
De Souza Guerra, C.
Cury, J.A.
De Almeida, A.P.
Barroso, R.C.
Gerlach, R.F.
Abstract: Like fluoride, lead (Pb) accumulates on the enamel surface pre-eruptively, but it is not yet known whether it also deposits on enamel while dental caries is developing. This study evaluates Pb distribution in bovine enamel slabs submitted to a pH-cycling regimen simulating the caries process. The slabs were subjected to 8 cycles of de-and remineralizing conditions, and Pb (as acetate salt) was added to the de-and remineralized solutions at concentrations of 30 μg/l (experimental group, E1) and 300 μg/l (experimental group, E2). The control group (C) consisted of solutions to which Pb was not added. After the pH cycling, 100-μm sections of the slabs were analyzed by polarizing microscopy, to observe the extent of caries-like lesions, and these sections were used for Pb estimation by Synchrotron radiation X-ray microfluorescence. Caries lesions were observed along all superficial enamel surfaces to an extent of 120 μm. A Pb concentration gradient was observed in enamel, which decreased toward dentine. The highest Pb signals were observed for group E2, and the differences were statistically significant at enamel depths of 0 (C vs. E2; p = 0.029) and 50 μm (C vs. E2 and E1 vs. E2; p = 0.029). In conclusion, this study suggests that if Pb is present in the oral environment, it may deposit in enamel during the caries process.
Subject: Esmalte dentário
Cárie dentária
Country: Suiça
Editor: Karger
Rights: Fechado
Identifier DOI: 10.1159/000330602
Date Issue: 2011
Appears in Collections:FOP - Artigos e Outros Documentos

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