Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/348820
Full metadata record
DC FieldValueLanguage
dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampLevy, Carlos Emilio-
dc.typeArtigopt_BR
dc.titleBalanoposthitis caused by pseudomonas aeruginosa co-producing metallo-beta-lactamase and 16S rRNA methylase in children with hematological malignanciespt_BR
dc.contributor.authorLincopan, Nilton-
dc.contributor.authorNeves, Patricia-
dc.contributor.authorMamizuka, Elsa M.-
dc.contributor.authorLevy, Carlos E.-
dc.subjectPseudomonas aeruginosapt_BR
dc.subject.otherlanguagePseudomonas aeruginosapt_BR
dc.description.abstractBalanoposthitis is defined as the inflammation of the glans penis and its foreskin. In the presence of other underlying medical conditions, this localized infection may spread systemically, serving as a source of fever and bacteremia in neutropenic males. Two rare cases of balanoposthitis caused by a clonally related Pseudomonas aeruginosa isolate co-producing the SPM-1 metallo-β-lactamase and the novel 16S rRNA methylase RmtD are described. Four multidrug-resistant (MDR) P. aeruginosa isolates were successively recovered from glans/foreskin swabs and urine cultures from two uncircumcised pediatric patients, one with Burkitt's non-Hodgkin's lymphoma and one with acute lymphoblastic leukemia. Clinically, preputial colonization by MDR P. aeruginosa evolved to severe balanoposthitis with glans/foreskin lesions as a source of fever. Combination therapy of ciprofloxacin and/or aztreonam (systemic) plus polymyxin B (topical) was effective once reversion of the neutropenic condition was achieved. Although P. aeruginosa remains an unusual cause of balanoposthitis, these cases should alert the physician to the potential pathogenicity of this bacterium. Furthermore, co-production of metallo-β-lactamase and 16S rRNA methylase has a potential impact on the empirical management of complicated infections caused by P. aeruginosapt_BR
dc.relation.ispartofInternational journal of infectious diseasespt_BR
dc.relation.ispartofabbreviationInt. j. infect. dis.pt_BR
dc.publisher.cityLondonpt_BR
dc.publisher.countryReino Unidopt_BR
dc.publisherElsevierpt_BR
dc.date.issued2010-
dc.language.isoengpt_BR
dc.description.volume14pt_BR
dc.description.issuenumber4pt_BR
dc.description.firstpagee344pt_BR
dc.description.lastpagee347pt_BR
dc.rightsAbertopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn1201-9712pt_BR
dc.identifier.eissn1878-3511pt_BR
dc.identifier.doi10.1016/j.ijid.2009.04.016pt_BR
dc.identifier.urlhttps://www.clinicalkey.com/#!/content/playContent/1-s2.0-S1201971209002136pt_BR
dc.description.sponsorshipFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPpt_BR
dc.description.sponsordocumentnumbernão tempt_BR
dc.date.available2020-09-08T12:56:01Z-
dc.date.accessioned2020-09-08T12:56:01Z-
dc.description.provenanceSubmitted by Mariana Aparecida Azevedo (mary1@unicamp.br) on 2020-09-08T12:56:01Z No. of bitstreams: 0. Added 1 bitstream(s) on 2021-01-04T15:12:49Z : No. of bitstreams: 1 000275794200012.pdf: 217672 bytes, checksum: e203489ae91a481db2a8a919e2bcda92 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-09-08T12:56:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2010en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/348820-
dc.contributor.departmentDepartamento de Patologia Clínicapt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.subject.keywordBalanitispt_BR
dc.subject.keywordMultidrug-resistantpt_BR
dc.subject.keywordNeutropenic patientspt_BR
dc.identifier.source000275794200012pt_BR
dc.creator.orcid0000-0002-4862-8900pt_BR
dc.type.formRelato de casopt_BR
Appears in Collections:FCM - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
000275794200012.pdf212.57 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.