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Type: Artigo
Title: Identification of a bioactive compound isolated from brazilian propolis type 6
Author: Castro, M.L.
Nascimento, A.M.
Ikegaki, M.
Costa-Neto, C.M.
Alencar, S.M.
Rosalen, P.L.
Abstract: A prenylated benzophenone, hyperibone A, was isolated from the hexane fraction of Brazilian propolis type 6. Its structure was determined by spectral analysis including 2D NMR. This compound exhibited cytotoxic activity against HeLa tumor cells (IC50 = 0.1756 μM), strong antimicrobial activity (MIC range-0.73-6.6 μg/mL; MBC range-2.92-106 μg/mL) against Streptococcus mutans, Streptococcus sobrinus, Streptococcus oralis, Staphylococcus aureus, and Actinomyces naeslundii, and the results of its cytotoxic and antimicrobial activities were considered good.
Subject: Benzofenonas
Atividade biológica
Country: Reino Unido
Editor: Elsevier
Rights: Fechado
Identifier DOI: 10.1016/j.bmc.2009.04.066
Date Issue: 2009
Appears in Collections:FOP - Artigos e Outros Documentos

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