Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/348759
Type: Artigo
Title: Characterization of language and reading skills in familial polymicrogyria
Author: Mesquita Oliveira, Ecila Paula
Vasconcelos Hage, Simone Rocha
Guimaraes, Catarina Abraao
Brandao-Almeida, Iara
Lopes-Cendes, Iscia
Guerreiro, Carlos Alberto
Sarmento Teixeira, Karine Couto
Montenegro, Maria Augusta
Cendes, Fernando
Guerreiro, Marilisa Mantovani
Abstract: Polymicrogyria (PMG) is a malformation of cortical development characterized by an excessive number of small gyri and abnormal cortical lamination, giving the cortical surface an irregular and gross appearance. The severity of clinical manifestations correlates with the extent of cortical involvement. The objective of the present study was to describe three families with linguistic features of developmental language disorder and reading impairment, and to establish a neuroanatomic correlation through neuroimaging. Subjects have been submitted to a comprehensive protocol including psychological assessment, language evaluation, neurological examination, and neuroimaging investigation. In our families, children usually had the diagnosis of developmental language disorder while adults had the diagnosis of reading impairment. MRI showed perisylvian polymicrogyria in several subjects of each family. Our data support the idea that there is a co-occurrence of developmental language disorder and reading impairment and both conditions may be associated with polymicrogyria
Subject: Transtornos do desenvolvimento da linguagem
Polimicrogiria
Country: Países Baixos
Editor: Elsevier
Rights: Fechado
Identifier DOI: 10.1016/j.braindev.2007.08.010
Address: https://www.sciencedirect.com/science/article/pii/S0387760407002069
Date Issue: 2008
Appears in Collections:FCM - Artigos e Outros Documentos

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