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Type: Artigo
Title: Economic impact of a rotavirus vaccine in Brazil
Author: Constenla, Dagna O
Linhares, Alexandre C
Rheingans, Richard D
Antil, Lynn R
Waldman, Eliseu A
Silva, Luiz J da
Abstract: The study was done to evaluate the cost-effectiveness of a national rotavirus vaccination programme in Brazilian children from the healthcare system perspective. A hypothetical annual birth-cohort was fol­lowed for a five-year period. Published and national administrative data were incorporated into a model to quantify the consequences of vaccination versus no vaccination. Main outcome measures included the reduction in disease burden, lives saved, and disability-adjusted life-years (DALYs) averted. A rotavirus vac­cination programme in Brazil would prevent an estimated 1,804 deaths associated with gastroenteritis due to rotavirus, 91,127 hospitalizations, and 550,198 outpatient visits. Vaccination is likely to reduce 76% of the overall healthcare burden of rotavirus-associated gastroenteritis in Brazil. At a vaccine price of US$ 7-8 per dose, the cost-effectiveness ratio would be US$ 643 per DALY averted. Rotavirus vaccination can reduce the burden of gastroenteritis due to rotavirus at a reasonable cost-effectiveness ratio
Subject: Rotavírus
Custos e análise de custo
Country: Reino Unido
Editor: BioMed Central
Rights: Aberto
Date Issue: 2008
Appears in Collections:FCM - Artigos e Outros Documentos

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