Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/348656
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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampSampaio-Barros, Percival Degrava-
dc.contributor.authorunicampConde, Roseneide Aparecida-
dc.contributor.authorunicampBonfiglioli, Rubens-
dc.contributor.authorunicampCostallat, Lilian Tereza Lavras-
dc.contributor.authorunicampSamara, Adil Muhib-
dc.contributor.authorunicampBértolo, Manoel Barros-
dc.typeArtigopt_BR
dc.titleFrequency of HLA-B27 and its alleles in patients with reiter syndrome: comparison with the frequency in other spondyloarthropathies and a healthy control populationpt_BR
dc.contributor.authorSampaio-Barros, Percival D.-
dc.contributor.authorConde, Roseneide A.-
dc.contributor.authorDonadi, Eduardo A.-
dc.contributor.authorBonfiglioli, Rubens-
dc.contributor.authorCostallat, Lilian T. L.-
dc.contributor.authorSamara, Adil M.-
dc.contributor.authorBértolo, Manoel B.-
dc.subjectEpidemiologiapt_BR
dc.subject.otherlanguageEpidemiologypt_BR
dc.description.abstractThis retrospective study analyzed the HLA-B*27 alleles in a group of 20 consecutive patients with the diagnosis of Reiter syndrome (RS) followed in a tertiary referral university hospital in Brazil, during the period 1990–2006, and compared the data with that observed in other patients with spondyloarthropathies followed at the same institution. Eight cases were associated to gastrointestinal infection, eight cases to previous urethritis, and four cases presented no established preceding infection. HLA-B*27 alleles were typed by polymerase chain reaction-amplified DNA hybridized with sequence-specific oligonucleotide probes (HLA-B*2701 to HLA-B*2721). They were compared to a group of 108 patients with ankylosing spondylitis (AS), 40 with undifferentiated spondyloarthropathy (uSpA) and 111 healthy controls. Among the 20 patients, 17 were HLA-B*27 positive (85%). Two HLA-B*27 alleles were observed: HLA-B*2705 (65%) and HLA-B*2702 (35%). In the other spondyloarthropathies, the observed alleles were HLA-B*2705 (90% in AS and 92.5% in uSpA), HLA-B*2702 (8% in AS and 5% in uSpA), HLA-B*2704 (1% in AS and 2.5% in uSpA) and HLA-B*2713 (1% in AS). Among the 111 healthy controls, 80% presented HLA-B*2705, followed by HLA-B*2702 in 10%, HLA-B*2703 in 6%, HLA-B*2707 in 3% and HLA-B*2713 in 1%. Concluding, in the HLA-B*27 positive patients with RS in this study there was predominance of HLA-B*2705 allele, in a lower frequency than that observed in patients with other spondyloarthropathies and healthy controlspt_BR
dc.relation.ispartofRheumatology internationalpt_BR
dc.relation.ispartofabbreviationRheumatol int.pt_BR
dc.publisher.cityHeidelbergpt_BR
dc.publisher.countryAlemanhapt_BR
dc.publisherSpringerpt_BR
dc.date.issued2008-
dc.date.monthofcirculationMar.pt_BR
dc.language.isoengpt_BR
dc.description.volume28pt_BR
dc.description.firstpage483pt_BR
dc.description.lastpage486pt_BR
dc.rightsFechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn0172-8172pt_BR
dc.identifier.eissn1437-160Xpt_BR
dc.identifier.doi10.1007/s00296-007-0441-3pt_BR
dc.identifier.urlhttps://link.springer.com/article/10.1007%2Fs00296-007-0441-3pt_BR
dc.description.sponsorshipFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPpt_BR
dc.description.sponsordocumentnumbernão tempt_BR
dc.date.available2020-09-03T17:37:14Z-
dc.date.accessioned2020-09-03T17:37:14Z-
dc.description.provenanceSubmitted by Mariana Aparecida Azevedo (mary1@unicamp.br) on 2020-09-03T17:37:14Z No. of bitstreams: 0. Added 1 bitstream(s) on 2021-01-04T15:12:33Z : No. of bitstreams: 1 000253204100013.pdf: 276512 bytes, checksum: c8eb3c963edde442290121d4b82dc514 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-09-03T17:37:14Z (GMT). No. of bitstreams: 0 Previous issue date: 2008en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/348656-
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentDepartamento de Clínica Médicapt_BR
dc.contributor.departmentDepartamento de Clínica Médicapt_BR
dc.contributor.departmentDepartamento de Clínica Médicapt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.subject.keywordReiter syndromept_BR
dc.subject.keywordHLA-B27pt_BR
dc.identifier.source000253204100013pt_BR
dc.creator.orcid0000-0001-9843-6686pt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcid0000-0002-3077-9479pt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcidsem informaçãopt_BR
dc.type.formRelato de casopt_BR
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