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Type: Artigo
Title: Alterations in cyclic GMP levels in preeclampsia may reflect increased B-type natriuretic peptide levels and not impaired nitric oxide activity
Author: Sandrim, Valeria C.
Palei, Ana C. T.
Sertorio, Jonas T.
Amaral, Lorena M.
Cavalli, Ricardo C.
Tanus-Santos, Jose E.
Abstract: We compared nitrite, B-type natriuretic peptide (BNP), and cGMP levels in preeclamptic with those found in healthy pregnant. We studied 21 healthy pregnant and 27 preeclamptic. Plasma cGMP and BNP levels were determined by ELISA. Nitrite levels were determined by chemiluminescence. Higher cGMP and BNP, and lower nitrite levels were found in preeclamptic versus healthy pregnant. Altered cGMP levels reflect increased BNP levels and not impaired nitric oxide activity in preeclampsia. (C) 2011 The Canadian Society of Clinical Chemists
Subject: Peptídeos natriuréticos
Country: Estados Unidos
Editor: Elsevier
Rights: Fechado
Identifier DOI: 10.1016/j.clinbiochem.2011.05.026
Date Issue: 2011
Appears in Collections:FCM - Artigos e Outros Documentos

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