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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampBahamondes, Luis Guillermo-
dc.typeArtigopt_BR
dc.titleEfficacy and tolerance of metronidazole and miconazole nitrate in treatment of vaginitispt_BR
dc.contributor.authorPeixoto, Fabio-
dc.contributor.authorCamargos, Aroldo-
dc.contributor.authorDuarte, Geraldo-
dc.contributor.authorLinhares, Iara-
dc.contributor.authorBahamondes, Luis-
dc.contributor.authorPetracco, Alvaro-
dc.subjectMetronidazolpt_BR
dc.subjectMiconazolpt_BR
dc.subject.otherlanguageMetronidazolept_BR
dc.subject.otherlanguageMiconazolept_BR
dc.description.abstractTo evaluate the efficacy and tolerability of a vaginal pessary containing 750 mg of metronidazole and 200 mg of miconazole nitrate used daily for 7 days in the treatment of vaginitis. Ninety‐two women with vaginitis participated in this phase 3 study using one vaginal pessary daily for 7 days. Gynecological and microbiological evaluations were carried out prior to and following treatment. Reductions occurred in symptoms and signs of vaginitis. Clinical cure rate was 87.7%, while the cure rates according to microscopy and Candida albicans culture were 81.8% and 73.9%, respectively. The cure rate for bacterial vaginosis was 75% and culture of Gardnerella vaginalis turned negative in 63.6% of cases following treatment. The medication was well tolerated. Use of a combination of 750 mg of metronidazole and 200 mg of miconazole in a single daily application was found to be effective in the treatment of the most common causes of vaginitispt_BR
dc.relation.ispartofInternational journal of gynecology and obstetricspt_BR
dc.relation.ispartofabbreviationInt. j. gynaecol. obstet.pt_BR
dc.publisher.cityChichesterpt_BR
dc.publisher.countryReino Unidopt_BR
dc.publisherWileypt_BR
dc.date.issued2008-
dc.date.monthofcirculationSept.pt_BR
dc.language.isoengpt_BR
dc.description.volume102pt_BR
dc.description.issuenumber3pt_BR
dc.description.firstpage287pt_BR
dc.description.lastpage292pt_BR
dc.rightsFechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn0020-7292pt_BR
dc.identifier.eissn1879-3479pt_BR
dc.identifier.doi10.1016/j.ijgo.2008.04.014pt_BR
dc.identifier.urlhttps://obgyn.onlinelibrary.wiley.com/doi/full/10.1016/j.ijgo.2008.04.014pt_BR
dc.date.available2020-09-03T14:48:54Z-
dc.date.accessioned2020-09-03T14:48:54Z-
dc.description.provenanceSubmitted by Susilene Barbosa da Silva (susilene@unicamp.br) on 2020-09-03T14:48:54Z No. of bitstreams: 0. Added 1 bitstream(s) on 2021-01-04T15:12:30Z : No. of bitstreams: 1 000259584400015.pdf: 216058 bytes, checksum: bf10598188197feb79fd89eb74bd2cf1 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-09-03T14:48:54Z (GMT). No. of bitstreams: 0 Previous issue date: 2008en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/348627-
dc.contributor.departmentDepartamento de Tocoginecologiapt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.subject.keywordVaginitispt_BR
dc.identifier.source000259584400015pt_BR
dc.creator.orcid0000-0002-7356-8428pt_BR
dc.type.formArtigopt_BR
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