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http://repositorio.unicamp.br/jspui/handle/REPOSIP/348627
Type: | Artigo |
Title: | Efficacy and tolerance of metronidazole and miconazole nitrate in treatment of vaginitis |
Author: | Peixoto, Fabio Camargos, Aroldo Duarte, Geraldo Linhares, Iara Bahamondes, Luis Petracco, Alvaro |
Abstract: | To evaluate the efficacy and tolerability of a vaginal pessary containing 750 mg of metronidazole and 200 mg of miconazole nitrate used daily for 7 days in the treatment of vaginitis. Ninety‐two women with vaginitis participated in this phase 3 study using one vaginal pessary daily for 7 days. Gynecological and microbiological evaluations were carried out prior to and following treatment. Reductions occurred in symptoms and signs of vaginitis. Clinical cure rate was 87.7%, while the cure rates according to microscopy and Candida albicans culture were 81.8% and 73.9%, respectively. The cure rate for bacterial vaginosis was 75% and culture of Gardnerella vaginalis turned negative in 63.6% of cases following treatment. The medication was well tolerated. Use of a combination of 750 mg of metronidazole and 200 mg of miconazole in a single daily application was found to be effective in the treatment of the most common causes of vaginitis |
Subject: | Metronidazol Miconazol |
Country: | Reino Unido |
Editor: | Wiley |
Rights: | Fechado |
Identifier DOI: | 10.1016/j.ijgo.2008.04.014 |
Address: | https://obgyn.onlinelibrary.wiley.com/doi/full/10.1016/j.ijgo.2008.04.014 |
Date Issue: | 2008 |
Appears in Collections: | FCM - Artigos e Outros Documentos |
Files in This Item:
File | Description | Size | Format | |
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000259584400015.pdf | 210.99 kB | Adobe PDF | View/Open |
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