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|Title:||Is a genome a codeword of anerror-correcting code?|
|Author:||Faria, Luzinete C. B.|
Rocha, Andrea S. L.
Kleinschmidt, Joao H.
Silva-Filho, Marcio C.
Herai, Roberto H.
Yamagishi, Michel E. B.
Palazzo Jr., Reginaldo
|Abstract:||Since a genome is a discrete sequence, the elements of which belong to a set of four letters, the question as to whether or not there is an error-correcting code underlying DNA sequences is unavoidable. The most common approach to answering this question is to propose a methodology to verify the existence of such a code. However, none of the methodologies proposed so far, although quite clever, has achieved that goal. In a recent work, we showed that DNA sequences can be identified as codewords in a class of cyclic error-correcting codes known as Hamming codes. In this paper, we show that a complete intron-exon gene, and even a plasmid genome, can be identified as a Hamming code codeword as well. Although this does not constitute a definitive proof that there is an error-correcting code underlying DNA sequences, it is the first evidence in this direction|
|Editor:||Public Library of Science|
|Appears in Collections:||FEEC - Artigos e Outros Documentos|
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