Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/348171
Full metadata record
DC FieldValueLanguage
dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampOliveira, Márcia Silva de-
dc.contributor.authorunicampD'Abreu, Anelyssa Cysne Frota-
dc.contributor.authorunicampFranca Junior, Marcondes Cavalcante-
dc.contributor.authorunicampLopes-Cendes, Íscia Teresinha-
dc.contributor.authorunicampCendes, Fernando-
dc.contributor.authorunicampCastellano, Gabriela-
dc.typeArtigopt_BR
dc.titleMRI‐Texture analysis of corpus callosum, thalamus, putamen, and caudate in Machado‐Joseph diseasept_BR
dc.contributor.authorde Oliveira, Marcia S.-
dc.contributor.authorD'Abreu, Anelyssa-
dc.contributor.authorFranca Junior, Marcondes C.-
dc.contributor.authorLopes-Cendes, Iscia-
dc.contributor.authorCendes, Fernando-
dc.contributor.authorCastellano, Gabriela-
dc.subjectDoença de Machado-Josephpt_BR
dc.subjectRessonância magnéticapt_BR
dc.subject.otherlanguageMachado-Joseph diseasept_BR
dc.subject.otherlanguageMagnetic resonancept_BR
dc.description.abstractTexture analysis (TA) is a branch of image processing, which attempts to convey "texture" information from digital images, such as magnetic resonance images (MRI). Machado-Joseph disease (MJD) affects mainly cerebellum and brainstem, but recent studies have shown that other cerebral structures may also be affected. To investigate subtle structural abnormalities in corpus callosum (CC), thalami, putamen, and caudate nuclei of patients with MJD using TA. METHODS Eighteen healthy volunteers and 18 patients with MJD were studied (mean age at disease onset = 34.7 years; disease duration = 9.6 years; mean expanded CAG in the MJD1 gene = 73). A TA approach based on the gray-level cooccurrence matrix was applied to T1-MRI. Regions of interest were manually segmented for each subject, and texture parameters were computed for each of the aforementioned anatomical structures. TA parameters showed differences between the 2 groups for the caudate nuclei, thalami, and putamen. No differences were found for the CC. TA was capable of detecting tissue alterations in MRI of patients with MJD. These alterations were in areas already shown to be affected by histopathological studies. In addition, we confirmed the thalamic involvement in patients with MJD, which had only been demonstrated in volumetric studiespt_BR
dc.relation.ispartofJournal of Neuroimagingpt_BR
dc.relation.ispartofabbreviationJ. Neuroimagingpt_BR
dc.publisher.cityHoboken, NJpt_BR
dc.publisher.countryEstados Unidospt_BR
dc.publisherWiley-Blackwellpt_BR
dc.date.issued2012-
dc.date.monthofcirculationJan.pt_BR
dc.language.isoengpt_BR
dc.description.volume22pt_BR
dc.description.issuenumber1pt_BR
dc.description.firstpage46pt_BR
dc.description.lastpage52pt_BR
dc.rightsFechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn1051-2284pt_BR
dc.identifier.eissn1552-6569pt_BR
dc.identifier.doi10.1111/j.1552-6569.2010.00553.xpt_BR
dc.identifier.urlhttps://onlinelibrary.wiley.com/doi/full/10.1111/j.1552-6569.2010.00553.xpt_BR
dc.date.available2020-08-27T19:23:05Z-
dc.date.accessioned2020-08-27T19:23:05Z-
dc.description.provenanceSubmitted by Cintia Oliveira de Moura (cintiaom@unicamp.br) on 2020-08-27T19:23:05Z No. of bitstreams: 0. Added 1 bitstream(s) on 2021-01-04T15:14:27Z : No. of bitstreams: 1 000299158500009.pdf: 417344 bytes, checksum: da09ce2da34aa8dd23eb143b0cf74d31 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-08-27T19:23:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2012en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/348171-
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentDepartamento de Neurologiapt_BR
dc.contributor.departmentDepartamento de Genética Médicapt_BR
dc.contributor.departmentDepartamento de Neurologiapt_BR
dc.contributor.departmentDepartamento de Raios Cósmicos e Cronologiapt_BR
dc.contributor.unidadeInstituto de Fisica Gleb Wataghinpt_BR
dc.contributor.unidadeFaculdade de Ciencias Medicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeInstituto de Física Gleb Wataghinpt_BR
dc.identifier.source000299158500009pt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcid0000-0001-6786-555Xpt_BR
dc.creator.orcid0000-0003-0898-2419pt_BR
dc.creator.orcid0000-0002-6221-6822pt_BR
dc.creator.orcid0000-0001-9336-9568pt_BR
dc.creator.orcid0000-0002-5927-487Xpt_BR
dc.type.formArtigopt_BR
Appears in Collections:IFGW - Artigos e Outros Documentos
FCM - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
000299158500009.pdf407.56 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.