Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/348121
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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampCipolli, José Alexandre Addêo-
dc.contributor.authorunicampFerreira-Sae, Maria Carolina Salmora-
dc.contributor.authorunicampMagalhães, José Alexandre Pio-
dc.contributor.authorunicampBellinazzi, Vera Regina-
dc.contributor.authorunicampNadruz Junior, Wilson-
dc.typeArtigopt_BR
dc.titleRelationship between serum uric acid and internal carotid resistive index in hypertensive women: a cross-sectional studypt_BR
dc.contributor.authorAddeo Cipolli, Jose Alexandre-
dc.contributor.authorFerreira-Sae, Maria Carolina-
dc.contributor.authorMartins, Rafael Prado-
dc.contributor.authorPio-Magalhaes, Jose Alexandre-
dc.contributor.authorBellinazzi, Vera Regina-
dc.contributor.authorMatos-Souza, Jose Roberto-
dc.contributor.authorNadruz Junior, Wilson-
dc.subjectAterosclerosept_BR
dc.subjectHiperuricemiapt_BR
dc.subjectRigidez vascularpt_BR
dc.subject.otherlanguageAtherosclerosispt_BR
dc.subject.otherlanguageHyperuricemiapt_BR
dc.subject.otherlanguageVascular stiffnesspt_BR
dc.description.abstractThe impact of serum uric acid (SUA) on arteries of hypertensive subjects remains to be fully established. This study investigated the relationship between SUA and carotid structural and hemodynamic parameters in hypertensive men and women. Three hundred and thirty eight patients (207 women and 131 men) were cross-sectionally evaluated by clinical, laboratory, hemodynamic and carotid ultrasound analysis. Common carotid diameters, circumferential wall tensions, Young's Elastic Modulus, Stiffness Index, Arterial Compliance and intima-media thickness (IMT) were determined. Internal carotid artery resistive index (ICRI), a hemodynamic measure that reflects local vascular impedance and microangiopathy, was also assessed. Univariate analysis showed no significant correlation of SUA with carotid diameters, elasticity/stiffness indexes, IMT and circumferential wall tensions in both genders. Conversely, SUA correlated with ICRI (r = 0.34; p < 0.001) in women, but not in men, and hyperuricemic women presented higher ICRI than normouricemic ones (0.684 +/- 0.007 vs. 0.649 +/- 0.004; p < 0.001). Stepwise and logistic regression analyses adjusted for potential confounding factors showed that ICRI was independently associated with SUA and hyperuricemia in women. This study demonstrated that SUA was associated with ICRI in hypertensive women, suggesting that there might gender-related differences in the relationship between SUA and vascular damage in subjects with systemic hypertensionpt_BR
dc.relation.ispartofBMC Cardiovascular Disorderspt_BR
dc.relation.ispartofabbreviationBMC Cardiovasc. Disord.pt_BR
dc.publisher.cityLondonpt_BR
dc.publisher.countryReino Unidopt_BR
dc.publisherBioMed Centralpt_BR
dc.date.issued2012-
dc.date.monthofcirculationJulypt_BR
dc.language.isoengpt_BR
dc.description.volume12pt_BR
dc.rightsFechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.eissn1471-2261pt_BR
dc.identifier.doi10.1186/1471-2261-12-52pt_BR
dc.identifier.urlhttps://bmccardiovascdisord.biomedcentral.com/articles/10.1186/1471-2261-12-52pt_BR
dc.description.sponsorshipCONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQpt_BR
dc.description.sponsorshipFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPpt_BR
dc.description.sponsordocumentnumber2010/16252-0pt_BR
dc.description.sponsordocumentnumber474966/2010-0; 303539/2010-0pt_BR
dc.date.available2020-08-27T14:38:57Z-
dc.date.accessioned2020-08-27T14:38:57Z-
dc.description.provenanceSubmitted by Cintia Oliveira de Moura (cintiaom@unicamp.br) on 2020-08-27T14:38:57Z No. of bitstreams: 0. Added 1 bitstream(s) on 2021-01-04T15:14:22Z : No. of bitstreams: 1 000307583700001.pdf: 324283 bytes, checksum: 1080b58a7b3fcf6c9eada59b3b744d8a (MD5)en
dc.description.provenanceMade available in DSpace on 2020-08-27T14:38:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2012en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/348121-
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentDepartamento de Enfermagempt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentDepartamento de Clínica Médicapt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.identifier.source000307583700001pt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcid0000-0001-6737-4187pt_BR
dc.creator.orcid0000-0002-0003-5102pt_BR
dc.type.formArtigo de pesquisapt_BR
dc.identifier.articleid52pt_BR
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