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Type: Artigo
Title: Alkaloids from the bark of Guatteria hispida and their evaluation as antioxidant and antimicrobial agents
Author: Costa, Emmanoel Vilaca
Pinheiro, Maria Lucia B.
Barison, Andersson
Campos, Francinete R.
Salvador, Marcos J.
Maia, Beatriz Helena L. N. S.
Cabral, Elaine C.
Eberlin, Marcos N.
Abstract: Phytochemical investigation of the bark of Guatteria hispida afforded three new alkaloids, 9-methoxy-O-methylmoschatoline (1), 9-methoxyisomoschatoline (2), and isocerasonine (3), along with 10 known alkaloids, 8-oxopseudopalmatine (4), O-methylmoschatoline (5), lysicamine (6), liriodenine (7), 10-methoxyliriodenine (8), nornuciferine (9), anonaine (10), xylopine (11), coreximine (12), and isocoreximine (13). The major compounds, 2, 6, 12, and 13, showed significant antioxidant capacity in the ORACFL assay. Compounds 5, 6, and 7 were active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5−100 μg mL−1
Subject: Carbono
Country: Estados Unidos
Editor: American Chemical Society
Rights: Fechado
Identifier DOI: 10.1021/np100013r
Date Issue: 2010
Appears in Collections:IQ - Artigos e Outros Documentos
IB - Artigos e Outros Documentos

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