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Type: Artigo
Title: Silk fibroin and sodium alginate blend: Miscibility and physical characteristics
Author: Moraes, Mariana Agostini de
Silva, Mariana Ferreira
Weska, Raquel Farias
Beppu, Marisa Masumi
Abstract: Films of silk fibroin (SF) and sodium alginate (SA) blends were prepared by solution casting technique. The miscibility of SF and SA in those blends was evaluated and scanning electron microscopy (SEM) revealed that SF/SA 25/75 wt.% blends underwent microscopic phase separation, resulting in globular structures composed mainly of SF. X-ray diffraction indicated the amorphous nature of these blends, even after a treatment with ethanol that turned them insoluble in water. Thermal analyses of blends showed the peaks of degradation of pristine SF and SA shifted to intermediate temperatures. Water vapor permeability, swelling capacity and tensile strength of SF films could be enhanced by blending with SA. Cell viability remained between 90 and 100%, as indicated by in vitro cytotoxicity test. The SF/SA blend with self-assembled SF globules can be used to modulate structural and mechanical properties of the final material and may be used in designing high performance wound dressing
Subject: Biopolímeros
Country: Países Baixos
Editor: Elsevier
Rights: Fechado
Identifier DOI: 10.1016/j.msec.2014.03.047
Date Issue: 2014
Appears in Collections:FEQ - Artigos e Outros Documentos

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