Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/347023
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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampBarbisan, Paulo Rodolfo Tagliari-
dc.contributor.authorunicampPinto, Roberto Damian Pacheco-
dc.contributor.authorunicampGusmão, Camillo Carneiro-
dc.contributor.authorunicampCastro, Rosane Silvestre de-
dc.contributor.authorunicampArieta, Carlos Eduardo Leite-
dc.typeArtigopt_BR
dc.titleCorneal collagen cross-linking in young patients for progressive keratoconuspt_BR
dc.contributor.authorTagliari, Barbisan, Paulo Rodolfo-
dc.contributor.authorPacheco, Pinto, Roberto Damian-
dc.contributor.authorCarneiro, Gusmão, Camillo-
dc.contributor.authorSilvestre, de Castro, Rosane-
dc.contributor.authorLeite, Arieta, Carlos Eduardo-
dc.subjectCeratoconept_BR
dc.subjectCórneapt_BR
dc.subjectColágenopt_BR
dc.subject.otherlanguageKeratoconuspt_BR
dc.subject.otherlanguageCollagenpt_BR
dc.subject.otherlanguageCornealpt_BR
dc.description.abstractThe goal of this study was to compare the effect of early corneal collagen cross-linking (CXL) intervention (before 17 years of age) with that of late intervention (after 17 years of age) on the characteristics and progression of keratoconus. One hundred five eyes of 94 patients with keratoconus undergoing treatment with CXL were included. The patients were divided into 2 groups by age: group 1 (mean age of 13.8 yrs; range 10–16) and group 2 (mean age of 21.5 yrs; range 17–36). Eyes were evaluated regarding best-corrected visual acuity (BCVA), refractive error, corneal endothelial cell density, and central corneal thickness, as well as using slit-lamp biomicroscopy, Goldmann tonometry, and the keratometry (Kmax, Ksteep, and Kflat parameters) test before CXL and at 1, 3, 6, and 12 months thereafter. The mean (SD) BCVA of group 1 was 0.45 (±0.25) before CXL and 0.56 (±0.29) 1 year after CXL (P = 0.030); mean (SD) Kmax, Ksteep, and Kflat were 58.47 (±7.2), 52.93 (±5.4), 47.22 (±4.2) before CXL respectively, and 58.21 (±7.7), 52.25 (±5.5), and 46.56 (±4.6) 1 year after CXL, respectively (P = 0.897, 0.481, and 0.491). The mean (SD) BCVA of group 2 was 0.50 (±0.30) before CXL and 0.56 (±0.32) 1 year thereafter (P = 0.346); mean (SD) Kmax, Ksteep, and Kflat were, respectively, 57.64 (±7.1), 54.02 (±6.2), and 48.60 (±4.1) before CXL and 56.46 (±8.0), 52.46 (±5.8), and 47.85 (±4.9) 1 year after CXL, respectively (P = 0.553, 0.258, and 0.640).The study showed no statistical differences between younger and older patients. These findings support the indication of CXL treatment in pediatric patients for early stabilization of the disease and better progress regarding BCVA and keratometry parameterspt_BR
dc.relation.ispartofCorneapt_BR
dc.relation.ispartofabbreviationCorneapt_BR
dc.publisher.cityPhiladelphia, PApt_BR
dc.publisher.countryEstados Unidospt_BR
dc.publisherWolters Kluwerpt_BR
dc.date.issued2020-
dc.date.monthofcirculationFeb.pt_BR
dc.language.isoengpt_BR
dc.description.volume39pt_BR
dc.description.issuenumber2pt_BR
dc.description.firstpage186pt_BR
dc.description.lastpage191pt_BR
dc.rightsFechadopt_BR
dc.sourceSCOPUSpt_BR
dc.identifier.issn0277-3740pt_BR
dc.identifier.eissn1536-4798pt_BR
dc.identifier.doi10.1097/ICO.0000000000002130pt_BR
dc.identifier.urlhttps://journals.lww.com/corneajrnl/Fulltext/2020/02000/Corneal_Collagen_Cross_Linking_in_Young_Patients.9.aspxpt_BR
dc.description.sponsorshipCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESpt_BR
dc.description.sponsordocumentnumber001pt_BR
dc.date.available2020-08-10T13:45:22Z-
dc.date.accessioned2020-08-10T13:45:22Z-
dc.description.provenanceSubmitted by Susilene Barbosa da Silva (susilene@unicamp.br) on 2020-08-10T13:45:21Z No. of bitstreams: 0en
dc.description.provenanceMade available in DSpace on 2020-08-10T13:45:22Z (GMT). No. of bitstreams: 0 Previous issue date: 2020en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/347023-
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentDepartamento de Oftalmologia e Otorrinolaringologiapt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.subject.keywordPediatricpt_BR
dc.subject.keywordOlderpt_BR
dc.identifier.source2-s2.0-85077403518pt_BR
dc.creator.orcid0000-0001-7680-5428pt_BR
dc.creator.orcid0000-0002-5541-9672pt_BR
dc.creator.orcidSem informaçãopt_BR
dc.creator.orcid0000-0002-1040-2391pt_BR
dc.creator.orcid0000-0003-3175-3147pt_BR
dc.type.formArtigopt_BR
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