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Type: Artigo
Title: Fibrous PCL/PLLA scaffolds obtained by rotary spinning and electrospinning
Author: Vida, Talita Almeida
Motta, Adriana Cristina
Santos Jr., Arnaldo Rodrigues
Cardoso, Guinea Brasil Camargo
Brito, Crystopher Cardoso de
Zavaglia, Cecília Amélia de Carvalho
Abstract: Rotary jet spinning (RJS) and electrospinning are techniques to obtain fibrous scaffolds. RJS is a simple method, which fabricates three-dimensional fibers by exploiting a high-speed rotating nozzle, creating a polymer jet which stretches until solidification, and does not require high voltage. In opposite, electrospinning technique needs the presence of an external electric field to create fiber from the polymeric jet solution. This article investigates both processes using two different biocompatible polymers: Poly(L-lactic acid) (PLLA) and Poly(ε-caprolactone) (PCL). Samples were characterized by scanning electron microscopy, thermogravimetric analysis, differential scanning calorimeter, and Fourier-transform infrared spectroscopy. Morphological observations showed the efficiency of both techniques in obtaining nanofibers. Thermal analyses of data indicate immiscible property of different blends and the total solvent evaporation. In vitro cytocompatibility test showed that RJS and electrospinning samples exhibited good cytocompatibility. Based on these results, it may be concluded that the fibers obtained with both technologies are non-cytotoxicity and with good biocompatibility, and might be suitable for applications as scaffold for cell growth
Subject: Nanofibras
Country: Brasil
Editor: UFSCar/Departamento de Engenharia de Materiais
Rights: Fechado
Identifier DOI: 10.1590/1980-5373-mr-2016-0969
Date Issue: 2018
Appears in Collections:FEM - Artigos e Outros Documentos

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