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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampGomes, Daniela Angerame Yela-
dc.typeArtigopt_BR
dc.titleSarcopenia in ovarian cancer patients, oncologic outcomes revealing the importance of clinical nutrition : review of literaturept_BR
dc.contributor.authorCianci, S.-
dc.contributor.authorRumolo, V.-
dc.contributor.authorRosati, A.-
dc.contributor.authorScaletta, G.-
dc.contributor.authorAlletti, S.G.-
dc.contributor.authorCerentini, T.M.-
dc.contributor.authorSleiman, Z.-
dc.contributor.authorLordelo, P.-
dc.contributor.authorAngerame, D.-
dc.contributor.authorGarganese, G.-
dc.contributor.authorUccella, S.-
dc.contributor.authorTarascio, M.-
dc.contributor.authorScambia, G.-
dc.subjectSarcopeniapt_BR
dc.subject.otherlanguageSarcopeniapt_BR
dc.description.abstractOvarian cancer is the leading cause of death among gynecological malignancies. Its usual clinical manifestation is at advanced stages, with nutritional impairment, weight loss, and a consequent decline in skeletal muscle mass and strength (defined as sarcopenia). The relationship between sarcopenia and decreased survival was demonstrated not only in ovarian cancer but also in other cancer types, such as hepatocellular, pancreatic, lung, colon, cervical, metastatic breast, and renal cancer. The aim of this study is to review the current evidence regarding the relationship between sarcopenia and the surgical and oncological outcomes in ovarian cancer patients. The systematic search was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRSIMA) statement. The terms “SARCOPENIA” AND “OVARIAN CANCER” were systematically used to search PubMed and Scopus databases. Original reports in English language were identified, with the purpose to include all relevant papers regarding the role of sarcopenia and indicators of skeletal muscle quality assessment in gynecological ovarian cancer. A total of 9 studies were considered eligible for the present review. The strength of recommendation was moderate and the level of evidence was low in all selected articles. No prospective studies were conducted and most of the papers were case-control series comparing ovarian cancer sarcopenic population vs. non sarcopenic population. Sarcopenia appears to have an important role in oncological outcomes of ovarian cancer patients. However, sarcopenia occurrence during disease history and mechanisms underlying the possible impairment in prognosis should be better investigated. Prospective trials are awaited in order to obtain a better insight in this topicpt_BR
dc.relation.ispartofCurrent harmaceutical designpt_BR
dc.publisher.citySharjahpt_BR
dc.publisher.countryEmirados Árabes Unidospt_BR
dc.publisherBentham Sciencept_BR
dc.date.issued2019-
dc.language.isoengpt_BR
dc.description.volume25pt_BR
dc.description.issuenumber22pt_BR
dc.description.firstpage2480pt_BR
dc.description.lastpage2490pt_BR
dc.rightsFechadopt_BR
dc.sourceSCOPUSpt_BR
dc.identifier.issn1381-6128pt_BR
dc.identifier.eissn1873-4286pt_BR
dc.identifier.doi10.2174/1381612825666190722112808pt_BR
dc.identifier.urlhttp://www.eurekaselect.com/173685/articlept_BR
dc.date.available2020-06-15T18:22:52Z-
dc.date.accessioned2020-06-15T18:22:52Z-
dc.description.provenanceSubmitted by Mariana Aparecida Azevedo (mary1@unicamp.br) on 2020-06-15T18:22:52Z No. of bitstreams: 0. Added 1 bitstream(s) on 2020-09-03T11:56:22Z : No. of bitstreams: 1 2-s2.0-85072942854.pdf: 2166572 bytes, checksum: 62601c59bbd1cc4db23722787d7d7ef8 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-06-15T18:22:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2019en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/343293-
dc.contributor.departmentDepartamento de Tocoginecologiapt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.subject.keywordOvarian cancerpt_BR
dc.subject.keywordNutritionpt_BR
dc.subject.keywordBody mass indexpt_BR
dc.subject.keywordNutritional impairmentpt_BR
dc.subject.keywordGynecological malignanciespt_BR
dc.identifier.source2-s2.0-85072942854pt_BR
dc.creator.orcid0000-0003-3889-4778pt_BR
dc.type.formArtigopt_BR
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