Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/343008
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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampSantos, Allan de Oliveira-
dc.contributor.authorunicampLima, Mariana da Cunha Lopes de-
dc.contributor.authorunicampEtchebehere, Elba Cristina Sa de Camargo-
dc.typeArtigopt_BR
dc.title18 F-FDG PET/CT performed immediately after percutaneous ablation to evaluate outcomes of the procedure : preliminary resultspt_BR
dc.title.alternative18 F-FDG PET/CT realizada imediatamente após ablação percutânea para avaliar os desfechos do procedimento : resultados preliminarespt_BR
dc.contributor.authorRomanato, J.-
dc.contributor.authorMenezes, M.R.-
dc.contributor.authorSantos, A.O.-
dc.contributor.authorBezerra, R.O.F.-
dc.contributor.authorLima, M.C.L.-
dc.contributor.authorEtchebehere, E.-
dc.subjectTomografia por emissão de pósitronspt_BR
dc.subject.otherlanguagePositron-emission tomographypt_BR
dc.description.abstractTo determine whether 18 F-fluorodeoxyglucose positron emission tomography/computed tomography performed immediately after percutaneous ablation ( iPA 18 F-FDG PET/CT) is useful in evaluating the outcomes of the procedure. This was a retrospective study of 20 patients (13 males, 7 females; mean age, 65.8 ± 12.1 years) submitted to percutaneous ablation of metastases. All of the lesions treated had shown focal uptake on a 18 F-FDG PET/CT scan obtained at baseline. The primary tumors were mainly colorectal cancer (in 45%) or lung cancer (in 40%). iPA 18 F-FDG PET/CT was performed to identify any residual viable tumor cells. The treatment was considered a success (no viable tumor cells present) if no uptake of 18 F-FDG was noted on the iPA 18 F-FDG PET/CT scan. Twenty-six lesions were submitted to percutaneous ablation with either cryoablation (n = 7) or radiofrequency ablation (n = 19). The mean lesion diameter was 2.52 ± 1.49 cm. For the detection of viable tumor cells, iPA 18 F-FDG PET/CT had a sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of 66.7%, 95%, 88.5%, 80%, and 90.5%, respectively. There was a significant correlation between the iPA 18 F-FDG PET/CT findings and the results of the follow-up studies (kappa = 0.66; p < 0.01). iPA 18 F-FDG PET/CT studies appear to constitute a useful means of evaluating the outcomes of percutaneous ablation. By detecting residual viable tumor cells, this strategy might allow early re-intervention, thus reducing morbidity. Studies involving larger numbers of patients are needed in order to confirm our findingspt_BR
dc.relation.ispartofRadiologia brasileirapt_BR
dc.relation.ispartofabbreviationRadiol. bras.pt_BR
dc.publisher.citySão Paulo, SPpt_BR
dc.publisher.countryBrasilpt_BR
dc.publisherColégio Brasileiro de Radiologia/Departamento da Associação Médica Brasileirapt_BR
dc.date.issued2019-
dc.date.monthofcirculationJan./Feb.pt_BR
dc.language.isoengpt_BR
dc.description.volume52pt_BR
dc.description.issuenumber1pt_BR
dc.description.firstpage24pt_BR
dc.description.lastpage32pt_BR
dc.rightsAbertopt_BR
dc.sourceSCOPUSpt_BR
dc.identifier.issn0100-3984pt_BR
dc.identifier.eissn1678-7099pt_BR
dc.identifier.doi10.1590/0100-3984.2018.0010pt_BR
dc.identifier.urlhttps://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842019000100024pt_BR
dc.date.available2020-06-09T16:49:55Z-
dc.date.accessioned2020-06-09T16:49:55Z-
dc.description.provenanceSubmitted by Mariana Aparecida Azevedo (mary1@unicamp.br) on 2020-06-09T16:49:55Z No. of bitstreams: 0. Added 1 bitstream(s) on 2020-09-03T11:56:06Z : No. of bitstreams: 1 2-s2.0-85063546165.pdf: 2143477 bytes, checksum: e08b7289e91a63e10d39d263755bbd37 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-06-09T16:49:55Z (GMT). No. of bitstreams: 0 Previous issue date: 2019en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/343008-
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.unidadeHospital das Clínicaspt_BR
dc.contributor.unidadeHospital das Clínicaspt_BR
dc.contributor.unidadeHospital das Clínicaspt_BR
dc.description.abstractalternativeDemonstrar se a tomografia por emissão de pósitrons acoplada a tomografia computadorizada usando-se fluorodesoxiglicose marcada com flúor-18 realizada imediatamente após ablação percutânea (iAP18F-FDG PET/CT) pode ser útil na avaliação do resultado desse tratamento. Foram avaliados, retrospectivamente, 20 pacientes (13 homens e 7 mulheres; média de idade: 65,8 ± 12,1 anos) submetidos a ablação percutânea de metástases apresentando captação de 18F-FDG no exame de PET/CT. Os tumores primários foram, principalmente, câncer colorretal (45%) ou câncer de pulmão (40%). A iAP18F-FDG PET/CT foi realizada para avaliar tumor residual viável. O tratamento foi considerado sucesso (sem lesão viável) se nenhuma captação de 18F-FDG fosse observada na iAP18F-FDG PET/CT. Vinte e seis lesões foram submetidas a ablação percutânea por meio de crioablação (n = 7) ou radiofrequência (n = 19). O tamanho médio das lesões era de 2,52 ± 1,49 cm. A iAP18F-FDG PET/CT detectou tumor viável com sensibilidade, especificidade, acurácia, valor preditivo positivo e valor preditivo negativo de 66,7%, 95%, 88,5%, 80% e 90,5%, respectivamente. Houve correlação significativa entre os achados da iAP18F-FDG PET/CT e os resultados do seguimento clínico dos pacientes (kappa = 0,66; p < 0,01). A iAP18F-FDG PET/CT é capaz de avaliar o resultado da ablação percutânea e poderá permitir reintervenção precoce de lesões residuais viáveis, reduzindo a morbidade. Um número maior de pacientes é necessário para confirmar esses achadospt_BR
dc.subject.keywordFluorodeoxyglucose F18pt_BR
dc.subject.keywordTomographypt_BR
dc.subject.keywordX-ray computed/methodspt_BR
dc.subject.keywordAblation techniquespt_BR
dc.subject.keywordCryosurgerypt_BR
dc.subject.keywordRadiofrequency ablationpt_BR
dc.identifier.source2-s2.0-85063546165pt_BR
dc.creator.orcid0000-0002-9192-6946pt_BR
dc.creator.orcid0000-0003-4839-6465pt_BR
dc.creator.orcid0000-0002-8632-5943pt_BR
dc.type.formArtigo originalpt_BR
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