Please use this identifier to cite or link to this item:
Type: Artigo de periódico
Title: Prevalence of codon 72 P53 polymorphism in Brazilian women with cervix cancer
Author: Brenna, Sylvia Michelina Fernandes
Silva, Ismael Dale Cotrin Guerreiro da
Zeferino, Luiz Carlos
Pereira, Julia
Martinez, Edson Zachaione
Syrjänen, Kari Juhani
Abstract: The p53 codon 72 polymorphism seems to be associated with HPV-carcinogenesis, although controversial data have been reported. A series of Brazilian women with cervix carcinomas were analyzed. Ninety-nine (67%) of 148 women were found to be homozygous (arg/arg) for the arginine polymorphism, and 49 (33%) were heterozygous (arg/pro). This polymorphism may be an important determinant of the risk for cervix cancer, but does not seem to be sufficient for carcinogenesis.
Subject: p53 polymorphism
codon 72
genetic polymorphism
cervix cancer
human papillomavirus
Editor: Sociedade Brasileira de Genética
Rights: aberto
Identifier DOI: 10.1590/S1415-47572004000400005
Date Issue: 1-Jan-2004
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

Files in This Item:
File Description SizeFormat 
S1415-47572004000400005.pdf382.48 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.