Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/342930
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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampGouvêa, Adriele Ferreira-
dc.contributor.authorunicampPalmier, Natália Rangel-
dc.contributor.authorunicampRibeiro, Ana Carolina Prado-
dc.contributor.authorunicampNormando, Ana Gabriela Costa-
dc.contributor.authorunicampGoes, Mario Fernando de-
dc.contributor.authorunicampLopes, Márcio Ajudarte-
dc.contributor.authorunicampSantos-Silva, Alan Roger-
dc.typeArtigopt_BR
dc.titleImpact of clustering oral symptoms in the pathogenesis of radiation caries : a systematic reviewpt_BR
dc.contributor.authorGouveâ Vasconcellos, A.F.-
dc.contributor.authorPalmier, N.R.-
dc.contributor.authorRibeiro, A.C.P.-
dc.contributor.authorNormando, A.G.C.-
dc.contributor.authorMorais-Faria, K.-
dc.contributor.authorGomes-Silva, W.-
dc.contributor.authorVechiato Filho, A.J.-
dc.contributor.authorDe Goes, M.F.-
dc.contributor.authorPaes Leme, A.F.-
dc.contributor.authorBrandão, T.B.-
dc.contributor.authorLopes, M.A.-
dc.contributor.authorMarsh, P.D.-
dc.contributor.authorSantos-Silva, A.R.-
dc.subjectCárie dentáriapt_BR
dc.subject.otherlanguageDental cariespt_BR
dc.description.abstractRadiation-related caries (RRC) is a disease with a high potential for destruction of the dentition, which impairs quality of life in head-and-neck (HN) cancer (HNC) patients who undergo radiotherapy. In light of the recently described "clustering of oral symptoms theory," the present systematic review (PROSPERO CRD42019132709) aims to assess HN and gastrointestinal (GI) symptom clusters among HNC patients and discusses how these indirect effects of cancer therapy play a pivotal role in the pathophysiology of RRC. The search was performed at PubMed, Scopus, and Embase and resulted in 11 studies that met the inclusion criteria. Data extraction was performed with respect to the presence of HN/GI symptom clusters among HNC patients. The methodological data of the studies included were assessed using the MAStARI and GRADE instruments. The most prevalent reported HN symptoms were dysphagia, xerostomia, and pain. Taste alterations and fatigue were also commonly reported by the patients. Loss of appetite and weight loss were regularly reported in the studies, as well as nausea and vomiting. The results of the present study suggest that HNC treatment generates clusters of oral symptoms, leading to dietary changes, impaired oral hygiene, enamel fragility, and a highly cariogenic oral environment, which may impact the risk for RRC. A better understanding of oral symptom clustering could be of considerable clinical significance for the oral health and quality of life of HNC patients. Therefore, contemporary protocols of RRC prevention must take this broader treatment scenario of symptom clusters such as oral side effects into accountpt_BR
dc.relation.ispartofCaries researchpt_BR
dc.relation.ispartofabbreviationCaries res.pt_BR
dc.publisher.cityBaselpt_BR
dc.publisher.countrySuiçapt_BR
dc.publisherKargerpt_BR
dc.date.issued2020-
dc.date.monthofcirculationJan.pt_BR
dc.language.isoengpt_BR
dc.rightsFechadopt_BR
dc.sourceSCOPUSpt_BR
dc.identifier.issn0008-6568pt_BR
dc.identifier.eissn1421-976Xpt_BR
dc.identifier.doi10.1159/000504878pt_BR
dc.identifier.urlhttps://www.karger.com/Article/FullText/504878pt_BR
dc.description.sponsorshipCONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQpt_BR
dc.description.sponsorshipCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESpt_BR
dc.description.sponsorshipFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPpt_BR
dc.description.sponsordocumentnumbernão tempt_BR
dc.description.sponsordocumentnumber1724203pt_BR
dc.description.sponsordocumentnumber2013/18402-8; 2016/22059-5; 2018/02233-6; 2018/04657-8pt_BR
dc.date.available2020-06-08T17:11:11Z-
dc.date.accessioned2020-06-08T17:11:11Z-
dc.description.provenanceSubmitted by Mariana Aparecida Azevedo (mary1@unicamp.br) on 2020-06-08T17:11:11Z No. of bitstreams: 0. Added 1 bitstream(s) on 2020-09-03T11:56:01Z : No. of bitstreams: 1 2-s2.0-85078364506.pdf: 576065 bytes, checksum: 178e5af69284850926a641f71f808d00 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-06-08T17:11:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2020en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/342930-
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentDepartamento de Diagnóstico Oralpt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentDepartamento de Odontologia Restauradorapt_BR
dc.contributor.departmentDepartamento de Diagnóstico Oralpt_BR
dc.contributor.departmentDepartamento de Diagnóstico Oralpt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.subject.keywordCancerpt_BR
dc.subject.keywordRadiotherapypt_BR
dc.subject.keywordChemotherapypt_BR
dc.subject.keywordXerostomiapt_BR
dc.identifier.source2-s2.0-85078364506pt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcid0000-0001-9588-6227pt_BR
dc.creator.orcid0000-0002-0127-7998pt_BR
dc.creator.orcid0000-0002-0307-4991pt_BR
dc.creator.orcid0000-0003-3433-9734pt_BR
dc.creator.orcid0000-0001-6677-0065pt_BR
dc.creator.orcid0000-0003-2040-6617pt_BR
dc.type.formArtigopt_BR
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