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dc.contributor.authorunicampDini, Caroline-
dc.contributor.authorunicampNagay, Bruna Egumi-
dc.contributor.authorunicampCordeiro, Jairo Matozinho-
dc.contributor.authorunicampRicomini Filho, Antônio Pedro-
dc.contributor.authorunicampBarão, Valentim Adelino Ricardo-
dc.titleUV-photofunctionalization of a biomimetic coating for dental implants applicationpt_BR
dc.contributor.authorDini, C.-
dc.contributor.authorNagay, B.E.-
dc.contributor.authorCordeiro, J.M.-
dc.contributor.authorda Cruz, N.C.-
dc.contributor.authorRangel, E.C.-
dc.contributor.authorRicomini-Filho, A.P.-
dc.contributor.authorde Avila, E.D.-
dc.contributor.authorBarão, V.A.R.-
dc.subjectMateriais biomiméticospt_BR
dc.subjectImplantes dentáriospt_BR
dc.subject.otherlanguageBiomimetic materialspt_BR
dc.subject.otherlanguageDental implantspt_BR
dc.description.abstractPhotofunctionalization mediated by ultraviolet (UV) rays changes the physico-chemical characteristics of titanium (Ti) and improves the biological activity of dental implants. However, the role of UV-mediated photofunctionalization of biofunctional Ti surfaces on the antimicrobial and photocatalytic activity remains unknown and was investigated in this study. Commercially pure titanium (cpTi) discs were divided into four groups: (1) machined samples without UV light application [cpTi UV−]; (2) plasma electrolytic oxidation (PEO) treated samples without UV light application [PEO UV−]; (3) machined samples with UV light application [cpTi UV+]; and (4) PEO-treated samples with UV light application [PEO UV+]. The surfaces were characterized according to their morphology, roughness, crystalline phase, chemical composition and wettability. The photocatalytic activity and proteins adsorption were measured. For the microbiological assay, Streptococcus sanguinis was grown on the disc surfaces for 1 h and 6 h, and the colony forming units and bacterial organization were evaluated. In addition, to confirm the non-cytotoxic effect of PEO UV +, human gingival fibroblast (HGF) cells were cultured in a monolayer onto each material surface and the cells viability and proliferation evaluated by a fluorescent cell staining method. PEO treatment increased the Ti surface roughness and wettability (p < 0.05). Photofunctionalization reduced the hydrocarbon concentration and enhanced human blood plasma proteins and albumin adsorption mainly for the PEO-treated surface (p < 0.05). PEO UV+ also maintained higher wettability values for a longer period and provided microbial reduction at 1 h of bacterial adhesion (p = 0.012 vs. PEO UV-). Photofunctionalization did not increase the photocatalytic activity of Ti (p > 0.05). Confocal microscopy analyses demonstrated that PEO UV+ had no cell damage effect on HGF cells growth even after 24 h of incubation. The photofunctionalization of a biofunctional PEO coating seems to be a promising alternative for dental implants as it increases blood plasma proteins adsorption, reduces initial bacterial adhesion and presents no cytotoxicity effectpt_BR
dc.relation.ispartofMaterials science and engineering C: materials for biological applicationspt_BR
dc.relation.ispartofabbreviationMater. sci. eng. C: mater. biol. appl.pt_BR
dc.publisher.countryPaíses Baixospt_BR
dc.description.provenanceSubmitted by Cintia Oliveira de Moura ( on 2020-06-01T19:37:42Z No. of bitstreams: 0. Added 1 bitstream(s) on 2020-09-03T11:56:27Z : No. of bitstreams: 1 2-s2.0-85078140660.pdf: 3949855 bytes, checksum: 6ccd5c374f974b07e0e4f56b80e1b4da (MD5)en
dc.description.provenanceMade available in DSpace on 2020-06-01T19:37:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2020en
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentDepartamento de Ciências Fisiológicaspt_BR
dc.contributor.departmentDepartamento de Prótese e Periodontiapt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.subject.keywordAerobic bacteriapt_BR
dc.subject.keywordMetal implantspt_BR
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