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http://repositorio.unicamp.br/jspui/handle/REPOSIP/341960
Type: | Artigo |
Title: | Effects of muscular strength training and growth hormone (GH) supplementation on femoral bone tissue: analysis by Raman spectroscopy, dual-energy X-ray absorptiometry, and mechanical resistance |
Author: | Castoldi, R.C. Ozaki, G.A.T. Garcia, T.A. Giometti, I.C. Koike, T.E. Camargo, R.C.T. dos Santos Pereira, J.D.A. Constantino, C.J.L. Louzada, M.J.Q. Camargo Filho, J.C.S. Belangero, W.D. |
Abstract: | The aim of the present study was to verify the effects of muscular strength training and growth hormone (GH) supplementation on femoral bone tissue by Raman spectroscopy (Raman), dual-energy X-ray absorptiometry (DXA), and mechanical resistance (F-max) analysis. A total of 40 male Wistar animals, 60 days old, were used. The animals were distributed into four groups: control (C), control with GH (GHC), muscular strength training (T), and muscular strength training with GH (GHT). Blood samples were collected for the quantification of creatine kinase (CK-MB) and the femurs were removed for analysis by Raman, DXA, and F-max. A more pronounced increase in the bone mineral components was verified in the T group, for all the variables obtained by the Raman (calcium, phosphate, amide, and collagen). In addition, for animals submitted to GH supplementation, there was a reduction in the variable bone mineral density (BMD) obtained by the DXA (p < 0.05). Finally, the animals that received GH supplementation presented a higher F-max, but without statistical significance (p > 0.05). It was concluded that animals that received GH supplementation demonstrated a decrease in BMD. In addition, T alone was able to promote increased calcium, phosphate, amide, and collagen compounds in bone tissue. |
Subject: | Somatotropina Femur |
Country: | Reino Unido |
Editor: | Springer |
Rights: | Fechado |
Identifier DOI: | 10.1007/s10103-019-02821-5 |
Address: | https://link.springer.com/article/10.1007%2Fs10103-019-02821-5 |
Date Issue: | 2019 |
Appears in Collections: | FCM - Artigos e Outros Documentos |
Files in This Item:
File | Description | Size | Format | |
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2-s2.0-85068162315.pdf | 766.58 kB | Adobe PDF | View/Open |
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