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|Title:||Development and testing of a high intensity electrical stimulator for isolated rat heart defibrillation|
de Oliveira, P.X.
|Abstract:||Researches with animal models have been carried out aim to study and optimize defibrillatory procedures. Isolated rat hearts stimulation by electric fields is one of the techniques used. Defibrillate the hearts in this type of preparation requires a high intensity stimulator able to provides pulses with high voltage levels and well defined durations. This work presents the development of a high intensity stimulator (HIS) that provides voltage pulses of 1 V to 1 kV and duration of 0.2–10 ms. The HIS consists mainly of a Flyback converter, high voltage capacitors and a firing circuit containing an Insulated Gate Bipolar Transistor (IGBT) controlled by a microcontroller. The energy stored in the capacitor was applied to a chamber containing isolated rat hearts in a Langendorff adapted preparation, which made possible to test the equipment. After applying the electric pulses, the residual capacitor voltage is dissipated in a power resistor. The stimulator presented satisfactory results since it was possible to defibrillate the hearts with quality and safety.|
|Appears in Collections:||FEEC - Artigos e Outros Documentos|
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