Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/341840
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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampTello Cajiao, John James-
dc.contributor.authorunicampBernal Rodriguez, Mario Antonio-
dc.typeArtigopt_BR
dc.titleDetermination of fast neutron RBE using a fully mechanistic computational modelpt_BR
dc.contributor.authorZabihi, Azam-
dc.contributor.authorTello, John-
dc.contributor.authorIncerti, Sebastien-
dc.contributor.authorFrancis, Ziad-
dc.contributor.authorForozani, Ghasem-
dc.contributor.authorSemsarha, Farid-
dc.contributor.authorMoslehi, Amir-
dc.contributor.authorBernal, Mario A.-
dc.subjectRadiobiologiapt_BR
dc.subjectNeutronspt_BR
dc.subject.otherlanguageRadiobiologypt_BR
dc.subject.otherlanguageNeutronspt_BR
dc.description.abstractThis work presents a model previously developed for estimating relative biological effectiveness (RBE) associated with high-LET particles. It is based on the combination of Monte Carlo simulations of particle interactions when traversing an atomic resolution DNA geometrical model. In addition, the model emulates the induction of lethal damage from the interaction of two sublethal lesions, taken as double-strand breaks. The Geant4-DNA package was used for simulations with liquid water as the transport medium. The RBE of neutron beams with energies ranging from 0.1 MeV up to 14 MeV was studied. The model succeeded in reproducing the general behavior of RBE as a function of neutron energy, including the RBE peak reported by experiments at approximately 0.4 MeV. Furthermore, the results of the model agree rather well with some experimental works. However, our results underestimate RBE for neutron energies above approximately 5 MeV due to the current limitations of Geant4-DNA for the tracking of heavy ions below 0.5 MeV/upt_BR
dc.relation.ispartofApplied radiation and isotopespt_BR
dc.relation.ispartofabbreviationAppl radiat isotpt_BR
dc.publisher.cityOxfordpt_BR
dc.publisher.countryReino Unidopt_BR
dc.publisherElsevierpt_BR
dc.date.issued2020-
dc.date.monthofcirculationFeb.pt_BR
dc.language.isoengpt_BR
dc.description.volume156pt_BR
dc.rightsFechadopt_BR
dc.sourceScopuspt_BR
dc.identifier.issn0969-8043pt_BR
dc.identifier.eissn1872-9800pt_BR
dc.identifier.doi10.1016/j.apradiso.2019.108952pt_BR
dc.identifier.urlhttps://www.sciencedirect.com/science/article/abs/pii/S0969804319306323pt_BR
dc.description.sponsorshipCONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQpt_BR
dc.description.sponsorshipFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPpt_BR
dc.description.sponsordocumentnumber306775/2015-8pt_BR
dc.description.sponsordocumentnumber2011/51594-2; 2015/21873-8; 2018/15316-7pt_BR
dc.date.available2020-05-20T19:23:34Z-
dc.date.accessioned2020-05-20T19:23:34Z-
dc.description.provenanceSubmitted by Thais de Brito Barroso (tbrito@unicamp.br) on 2020-05-20T19:23:34Z No. of bitstreams: 0. Added 1 bitstream(s) on 2020-08-27T19:15:21Z : No. of bitstreams: 1 2-s2.0-85075471233.pdf: 698317 bytes, checksum: d17c485c7df339e8c5ad8527d9261253 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-05-20T19:23:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2020en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/341840-
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentDepartamento de Física Aplicadapt_BR
dc.contributor.unidadeInstituto de Física Gleb Wataghinpt_BR
dc.contributor.unidadeInstituto de Física Gleb Wataghinpt_BR
dc.subject.keywordMonte Carlopt_BR
dc.subject.keywordRBEpt_BR
dc.identifier.source2-s2.0-85075471233pt_BR
dc.creator.orcid0000-0002-7927-9467pt_BR
dc.creator.orcid0000-0002-8305-5298pt_BR
dc.type.formArtigopt_BR
dc.identifier.articleid108952pt_BR
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