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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampLima, Débora Alves Nunes Leite-
dc.typeArtigopt_BR
dc.titleViscosity of chitosan impacts the efficacy of F/Sn containing toothpastes against erosive/abrasive wear in enamelpt_BR
dc.contributor.authorPini, N.I.P.-
dc.contributor.authorLima, D.A.N.L.-
dc.contributor.authorLuka, B.-
dc.contributor.authorGanss, C.-
dc.contributor.authorSchlueter, N.-
dc.subjectQuitosanapt_BR
dc.subject.otherlanguageChitosanpt_BR
dc.description.abstractChitosan (Ch) in F/Sn-toothpastes can increase toothpastes’ anti-erosive efficacy. Whether efficacy can be further increased by changing chitosan's viscosity was study aim. Methods: 192 human enamel specimens were assigned to 2 × 6 groups (n = 16 each): Four F/Sn (500 ppm F−, 800 ppm Sn2+) toothpastes with chitosan (0.5 %, viscosity 50, 500, 1000 or 2000 mPas), negative-control (no F/Sn/chitosan), positive-control (F/Sn, no chitosan). The study was conducted in two experiments (E1/E2). Specimens were cyclically demineralised (10 d, 6 × 2 min/d; 0.5 % citric acid); half of groups (E1) was exposed to toothpaste slurries (2 × 2 min/d), the other half was additionally brushed (2 × 15 s/d, E2). Tissue loss (mean ± SD, μm) was quantified profilometrically. Element analysis (EDX, wt%) on specimen surfaces and on toothpastes’ particulate fraction and SEM analysis of specimen surfaces were performed. Results: Tissue loss in negative-controls (E1/E2) was 4.96 ± 1.55/12.76 ± 2.45. Toothpastes with active agents (AA) reduced tissue loss compared to negative-control (p < 0.0001). E1: All AA caused precipitates, being the thickest after Ch500. Chitosan increased carbon retention, not tin retention. E2: Only Ch1000 increased efficacy (-0.97 ± 4.48) compared to positive-control (2.98 ± 1.32; p = 0.05). EDX showed comparable carbon values in all AA; tin content was higher in Ch1000 (6.5 ± 3.4) compared to other AA (range: 3.8 ± 0.3–4.3 ± 1.3). On abrasives, tin adsorption was decreased by all chitosans. SEM revealed minor structural differences. Conclusions: Chitosan viscosity has impact on efficacy of F/Sn toothpastes. Under erosive/abrasive conditions Ch1000 showed the best protective effect with higher tin retention on surfaces and lower tin absorption by abrasives. Clinical significance: The biopolymer chitosan shows protective effect against enamel erosion and erosion/abrasion when used in an F/Sn toothpaste with specific viscositypt_BR
dc.relation.ispartofJournal of dentistrypt_BR
dc.relation.ispartofabbreviationJ. dent.pt_BR
dc.publisher.cityLondonpt_BR
dc.publisher.countryReino Unidopt_BR
dc.publisherElsevierpt_BR
dc.date.issued2020-
dc.date.monthofcirculationJan.pt_BR
dc.language.isoengpt_BR
dc.description.volume92pt_BR
dc.rightsFechadopt_BR
dc.sourceSCOPUSpt_BR
dc.identifier.issn0300-5712pt_BR
dc.identifier.eissn1879-176Xpt_BR
dc.identifier.doi10.1016/j.jdent.2019.103247pt_BR
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0300571219302520pt_BR
dc.description.sponsorshipCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESpt_BR
dc.description.sponsordocumentnumber9999.010710/2014-00pt_BR
dc.date.available2020-05-20T16:59:29Z-
dc.date.accessioned2020-05-20T16:59:29Z-
dc.description.provenanceSubmitted by Sanches Olivia (olivias@unicamp.br) on 2020-05-20T16:59:29Z No. of bitstreams: 0. Added 1 bitstream(s) on 2020-08-27T19:15:29Z : No. of bitstreams: 1 2-s2.0-85076205913.pdf: 1567276 bytes, checksum: 8b8f1532370a25568d973747e12bdb41 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-05-20T16:59:29Z (GMT). No. of bitstreams: 0 Previous issue date: 2020en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/341807-
dc.contributor.departmentDepartamento de Odontologia Restauradorapt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.subject.keywordErosive tooth wearpt_BR
dc.subject.keywordEnamelpt_BR
dc.subject.keywordProfilometrypt_BR
dc.subject.keywordEDXSEMpt_BR
dc.identifier.source2-s2.0-85076205913pt_BR
dc.creator.orcid0000-0001-5457-3347pt_BR
dc.type.formArtigopt_BR
dc.identifier.articleid103247pt_BR
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