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Type: Artigo
Title: Sliding mode control in a mathematical model to chemoimmunotherapy: the occurrence of typical singularities
Author: Rodrigues, Diego S.
Mancera, Paulo F. A.
Carvalho, Tiago
Gonçalves, Luiz Fernando
Abstract: The application of sliding mode control and piecewise smooth vector fields in cancer is an incipient research area. Here we propose a piecewise dynamics to explore chemoimmunotherapeutic strategies. We investigate the dynamic behavior of the discontinuous mathematical model and we observe the occurrence of typical singularities. The on-off treatment strategies are defined in terms of a time-dependent variable such as the number of cancer or immune cells
Subject: Câncer
Country: Estados Unidos
Editor: Elsevier
Rights: Fechado
Identifier DOI: 10.1016/j.amc.2019.124782
Date Issue: 2019
Appears in Collections:FT - Artigos e Outros Documentos

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