Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/341585
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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampDiniz, Tiago Bezerra de Freitas-
dc.contributor.authorunicampJesus, Rafael Nascimento de-
dc.contributor.authorunicampJimenez, Laísa Simakawa-
dc.contributor.authorunicampPareja, José Carlos-
dc.contributor.authorunicampChaim, Elinton Adami-
dc.contributor.authorunicampCazzo, Everton-
dc.typeArtigopt_BR
dc.titleNon-alcoholic fatty liver disease is associated with impairment of ejection fraction among individuals with obesity undergoing bariatric surgery: results of a cross-sectional studypt_BR
dc.contributor.authorDiniz, Tiago Bezerra de Freitas-
dc.contributor.authorJesus, Rafael Nascimento de-
dc.contributor.authorJimenez, Laísa Simakawa-
dc.contributor.authorPareja, José Carlos-
dc.contributor.authorChaim, Elinton Adami-
dc.contributor.authorCazzo, Everton-
dc.subjectObesidadept_BR
dc.subjectCirurgia bariátricapt_BR
dc.subject.otherlanguageObesitypt_BR
dc.subject.otherlanguageBariatric surgerypt_BR
dc.description.abstractThe relationship between non-alcoholic fatty liver disease (NAFLD) and myocardial function seems to be more than just the effect of mutual metabolic risk factors. Objective: To determine whether there is a significant association between NAFLD assessed by means of liver biopsy and left ventricular function expressed by the estimated ejection fraction among individuals with obesity. Methods: This is a cross-sectional study which enrolled individuals who consecutively underwent bariatric surgery. NAFLD was assessed by means of liver biopsies which were systematically collected during the procedures. The estimated ejection fraction was obtained by means of transthoracic echocardiograms. The main outcome evaluated was a possible association between NAFLD features and ejection fraction. The results of liver biopsies and the respective degrees of severity of each NAFLD feature were also correlated with the ejection fraction and main anthropometric, biochemical, and clinical variables. Results: Of 112 individuals, 86.6% were female and the mean age was 38.5 ± 9.3 years. It was observed that the average estimated ejection fraction (EEF) was significantly lower among individuals with liver fibrosis (67.6 ± 5.5% vs. 70.8 ± 4.9%, p = 0.008). After adjustment for confounding variables in a multivariate model, the degree of liver fibrosis was independently associated with the EEF (R = − 0.3, p = 0.02). Conclusion: Among individuals with morbid obesity, the findings of this study are suggestive that liver fibrosis confirmed by histopathological examination is associated with a slight impairment of left ventricular function. Further studies are needed to confirm this associationpt_BR
dc.relation.ispartofObesity surgerypt_BR
dc.relation.ispartofabbreviationObes. surg.pt_BR
dc.publisher.cityNew York, NYpt_BR
dc.publisher.countryEstados Unidospt_BR
dc.publisherSpringerpt_BR
dc.date.issued2020-
dc.date.monthofcirculationFeb.pt_BR
dc.language.isoengpt_BR
dc.description.volume30pt_BR
dc.description.issuenumber2pt_BR
dc.description.firstpage456pt_BR
dc.description.lastpage460pt_BR
dc.rightsFechadopt_BR
dc.sourceScopuspt_BR
dc.identifier.issn0960-8923pt_BR
dc.identifier.eissn1708-0428pt_BR
dc.identifier.doi10.1007/s11695-019-04179-7pt_BR
dc.identifier.urlhttps://link.springer.com/article/10.1007/s11695-019-04179-7pt_BR
dc.date.available2020-05-16T19:04:57Z-
dc.date.accessioned2020-05-16T19:04:57Z-
dc.description.provenanceSubmitted by Thais de Brito Barroso (tbrito@unicamp.br) on 2020-05-16T19:04:57Z No. of bitstreams: 0en
dc.description.provenanceMade available in DSpace on 2020-05-16T19:04:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2020en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/341585-
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentDepartamento de Cirurgiapt_BR
dc.contributor.departmentDepartamento de Cirurgiapt_BR
dc.contributor.departmentDepartamento de Cirurgiapt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.subject.keywordFatty liverpt_BR
dc.subject.keywordEchocardiographypt_BR
dc.subject.keywordLiver diseasespt_BR
dc.identifier.source2-s2.0-85073925799pt_BR
dc.creator.orcidSem informaçãopt_BR
dc.creator.orcidSem informaçãopt_BR
dc.creator.orcidSem informaçãopt_BR
dc.creator.orcid0000-0001-8993-7147pt_BR
dc.creator.orcid0000-0003-4627-0631pt_BR
dc.creator.orcid0000-0002-5804-1580pt_BR
dc.type.formArtigopt_BR
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