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Type: Outro documento
Title: Using RNA interference for purinoceptor knockdown in vivo
Author: Amorim, Rebeca Padrão
Cendes, Iscia Teresinha Lopes
Fernandes, Maria Jose da Silva
Abstract: RNA interference (RNAi) is a powerful post-transcriptional gene silencing (PTGS) induced by small double-stranded RNA (dsRNA). The method allows silencing of genes of interest by translation inhibition or by mRNA degradation. In this chapter, we provide a brief overview of the mechanisms involved in each step of gene silencing. A nonviral infusion of short siRNA into ventricular system of rats was used to study purinoceptor in the rat brain
Subject: RNA
Receptores purinergicos
Hipocampo (Cérebro)
Country: Estados Unidos
Editor: Springer
Rights: Fechado
Identifier DOI: 10.1007/978-1-4939-9717-6_5
Date Issue: Oct-2019
Appears in Collections:FCM - Artigos e Outros Documentos

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