Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/341369
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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampDias, Viviane Liotti-
dc.contributor.authorunicampGilioli, Rovilson-
dc.contributor.authorunicampPassos, Luiz Augusto Corrêa-
dc.typeArtigopt_BR
dc.titleVirulence of Trypanosoma cruzi from vector and reservoir in in natura açaí pulp resulting in food-borne acute Chagas disease at Pará State, Brazilpt_BR
dc.contributor.authorLabello Barbosa, R.-
dc.contributor.authorDias, V.L.-
dc.contributor.authorLorosa, E.S.-
dc.contributor.authorde Góes Costa, E.-
dc.contributor.authorPereira, K.S.-
dc.contributor.authorGilioli, R.-
dc.contributor.authorGuaraldo, A.M.A.-
dc.contributor.authorPassos, L.A.C.-
dc.subjectTrypanosoma cruzipt_BR
dc.subject.otherlanguageTrypanosoma cruzipt_BR
dc.description.abstractIn recent decades some outbreaks of food-borne acute Chagas disease (ACD) in humans were identified by clinical and epidemiological characterization after association through the ingestion of açaí pulp probably contaminated with Trypanosoma cruzi. Whereas Belém and Abaetetuba stood out as important risk regions for disease transmission, the importance of Rhodnius pictipes, and Philander opossum for the biological cycle of T. cruzi, and data from agribusiness market of açaí to study T. cruzi from vector and reservoir of the Brazilian Amazon region is critical for this context. Thus, the purpose of this study was to verify the infective capacity and the virulence of T. cruzi in açaí pulp from vector and reservoir at Pará State experimentally. Methods: 10 5 T. cruzi I in in natura açaí pulp from Belém at Pará State, at room temperature, after forced sieving, by intraperitoneal, gavage or oral route of inoculation in B6.129S7Rag1 −/−tmMom /J Unib allowed food-borne ACD analysis using common light microscopy. Principal findings: T. cruzi in in natura açaí pulp from R. pictipes (Val-De-Cans Forest, Belém, and Ajuaí River, Abaetetuba, Pará), and P. opossum (Combu Island, Belém, Pará) caused ACD and death between 17 and 52 days after experimental infections in murine immunodeficient hosts. Conclusions: T. cruzi from different sources and locations at Pará State in in natura açaí pulp retained its infective capacity and virulence, and can cause new outbreaks of ACD by oral transmission. Additionally, quality basic education will facilitate efficient hygiene practices throughout the açaí productive chain can eradicate food-borne ACD in the coming decadespt_BR
dc.relation.ispartofExperimental parasitologypt_BR
dc.relation.ispartofabbreviationExp. parasitol.pt_BR
dc.publisher.cityMaryland Heights, MOpt_BR
dc.publisher.countryEstados Unidospt_BR
dc.publisherElsevierpt_BR
dc.date.issued2019-
dc.date.monthofcirculationFeb.-
dc.language.isoengpt_BR
dc.description.volume197pt_BR
dc.description.firstpage68pt_BR
dc.description.lastpage75pt_BR
dc.rightsFechadopt_BR
dc.sourceSCOPUSpt_BR
dc.identifier.issn0014-4894pt_BR
dc.identifier.eissn1090-2449pt_BR
dc.identifier.doi10.1016/j.exppara.2018.10.012pt_BR
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0014489418302650pt_BR
dc.description.sponsorshipCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESpt_BR
dc.description.sponsordocumentnumbersem informaçãopt_BR
dc.date.available2020-05-13T22:04:42Z-
dc.date.accessioned2020-05-13T22:04:42Z-
dc.description.provenanceSubmitted by Sanches Olivia (olivias@unicamp.br) on 2020-05-13T22:04:42Z No. of bitstreams: 0. Added 1 bitstream(s) on 2020-08-27T19:17:49Z : No. of bitstreams: 1 2-s2.0-85061230463.pdf: 640273 bytes, checksum: 53694c4fed79f72757c694da39ecdf99 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-05-13T22:04:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2019en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/341369-
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.unidadeCentro Multidisciplinar para Investigação Biológica na Área da Ciência em Animais de Laboratóriopt_BR
dc.contributor.unidadeCentro Multidisciplinar para Investigação Biológica na Área da Ciência em Animais de Laboratóriopt_BR
dc.contributor.unidadeCentro Multidisciplinar para Investigação Biológica na Área da Ciência em Animais de Laboratóriopt_BR
dc.subject.keywordRhodnius pictipespt_BR
dc.subject.keywordPhilander opossumpt_BR
dc.subject.keywordAçaí pulppt_BR
dc.subject.keywordFood-borne acute Chagas diseasept_BR
dc.subject.keywordPará Statept_BR
dc.identifier.source2-s2.0-85061230463pt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcid0000-0002-7767-691Xpt_BR
dc.creator.orcidsem informaçãopt_BR
dc.type.formArtigopt_BR
dc.description.sponsorNoteWe thank the Secretaria de Estado de Saúde Pública do Pará(SESPA), and the Fundação Oswaldo Cruz (Fiocruz) for the servicesprovided and resources; the Centro Multidisciplinar para InvestigaçãoBiológica na Área da Ciência de Animais de Laboratório (Cemib/Unicamp) for the infrastructure for this research, and the Coordenaçãode Aperfeiçoamento de Pessoal de Nível Superior (Capes) to providefinancial support for this studypt_BR
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