Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/340530
Type: Artigo
Title: Heat shock factor (HSF): the promoter of chaperone genes. A mini review
Author: Quel, Natalia Galdi
Ramos, Carlos H. I.
Abstract: Protein homeostasis, or proteostasis, is required for proper cell function and thus must be under tight maintenance in all circumstances. In crowded cell conditions, protein folding is sometimes unfavorable, and this condition is worsened during stress situations. Cells cope with such stress through the use of a Protein Quality Control system, which uses molecular chaperones and heat shock proteins as its major players. This system aids with folding, avoiding misfolding and/or reversing aggregation. A pivotal regulator of the response to heat stress is Heat Shock Factor, which is recruited to the promoters of the chaperone genes, inducting their expression. This mini review aims to cover our general knowledge on the structure and function of this factor
Subject: Proteínas de choque térmico
Country: Emirados Árabes Unidos
Editor: Bentham Science
Rights: Fechado
Identifier DOI: 10.2174/1570164615666180713095309
Address: http://www.eurekaselect.com/163741/article
Date Issue: 2019
Appears in Collections:IQ - Artigos e Outros Documentos
IB - Artigos e Outros Documentos

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