Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/340275
Type: Artigo
Title: Management of women affected by endometriosis : are we stepping forward?
Author: Guardo, Federica Di
Shah, Mohsin
Cerana, Maria Cecilia
Biondi, Antonio
Karaman, Erbil
Török, Péter
Yela, Daniela A.
Giampaolino, Pierluigi
Marín-Buck, Alejandro
Laganà, Antonio Simone
Abstract: Endometriosis is an estrogen-dependent chronic disease defined by the presence of endometrial-like tissue, glands and stroma in ectopic areas. Among all the pathogenic theories proposed to explain the origin of the disease, a pivotal role for immune, hormonal, and epigenetic disbalances have been hypothesized. Endometriosis affects up to 10%–15% of women in reproductive age and represents one of the most common gynecological causes of severe pelvic pain. The main symptoms reported by patients are dysmenorrhea and deep dyspareunia. Although the histological confirmation has been commonly considered mandatory, to date the possibility offered by the improvement in imagining techniques allows to make a proper diagnosis of the disease in most of the cases. Medical therapy represents only a symptomatic treatment and not the definitive solution. The aim of the hormonal therapy is to abolish the menstrual flow using progestin, oral contraceptives, and gonadotropin-releasing hormone agonists to reduce pelvic pain. Surgical treatment consisting of laparoscopy has the goal of abolishing pain and may be conservative or radical in nature depending on the patients’ desire of spontaneous conception in the future. Radical surgery seems to be associated with a higher percentage of pain relief as well as higher recurrence rates. Due to the worldwide acceptance and the ongoing evolution of minimally invasive surgery to treat both benign and malignant diseases, future investigations may be conducted to consider this approach to save the function of all the organs involved by the disease and to reduce post-operative discomfort and psychological impact
Subject: Endometriose
Infertilidade
Etiologia
Tratamento
Procedimentos cirúrgicos minimamente invasivos
Country: Reino Unido
Editor: Sage
Rights: Fechado
Identifier DOI: 10.1177/2284026519841520
Address: https://journals.sagepub.com/doi/full/10.1177/2284026519841520
Date Issue: Jun-2019
Appears in Collections:FCM - Artigos e Outros Documentos

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