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Type: Artigo
Title: Leiomyomatous hamartomas of the oral cavity: clinicopathological and immunohistochemical features of 4 cases and literature review
Author: Sanchez-Romero, Celeste
Ferreti Bonan, Paulo Rogerio
Pires, Fabio Ramoa
Silva-Junior, Geraldo Oliveira
Azanero, Wilson Delgado
de Almeida, Oslei Paes
da Cruz Perez, Danyel Elias
Abstract: To present 4 new cases of oral leiomyomatous hamartomas (OLH), describing its clinical, microscopical, and immunohistochemical features, and a literature review. Methods. The OLH cases were retrieved from the files of 2 Brazilian and 1 Peruvian oral pathology services. Clinical data were obtained from the pathology reports. Microscopical features were reviewed, and immunohistochemical reactions were performed. A review of the English-language literature about OLH was done. Results. The sample was composed of 3 females (4-, 10-, and 15-year-old) and 1 male (3-year-old). Three cases affected the dorsum of the tongue and one the incisive papilla, and all presented sessile or pedunculated smooth nodules. Microscopically, the lesions were composed of varying-size fascicles of smooth muscle fibers in a fibrous connective tissue background. Immunohistochemistry revealed positivity of the smooth muscle bundles for myogenic markers. The English-language literature review revealed 38 OLH cases reported, most were congenital or diagnosed up to 5 years old. The main locations were tongue and anterior maxilla. Conclusions. Although OLH is a rare lesion, it must be considered in the differential diagnosis of midline tongue or maxillary masses in newborns, infants, and youngsters
Subject: Imuno-histoquímica
Country: Estados Unidos
Editor: Sage
Rights: Fechado
Identifier DOI: 10.1177/1066896919843337
Date Issue: 2019
Appears in Collections:FOP - Artigos e Outros Documentos

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