Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/340186
Full metadata record
DC FieldValueLanguage
dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampMafra, Ana Carolina Cintra Nunes-
dc.typeArtigopt_BR
dc.titleSeveral faces of glutaminase regulation in cellspt_BR
dc.contributor.authorMafra, Ana C. P.-
dc.contributor.authorDias, Sandra M. G.-
dc.subjectGlutaminasept_BR
dc.subject.otherlanguageGlutaminasept_BR
dc.description.abstractThe cancer target glutaminase (GLS) has proven to be a fascinating protein. Since it was first described to be regulated by the oncogene Myc 10 years ago, several other transcriptional, posttranscriptional, and posttranslational regulatory mechanisms have emerged, and the list is growing. A recent study by Deng and colleagues revealed that an antisense (AS) long noncoding RNA named GLS-AS, which is negatively regulated by Myc, downregulates GLS in pancreatic cancer. The Myc/GLS-AS/GLS regulatory axis is activated by nutrient stress, which is important for the often hypovascular pancreatic cancer, displaying the significance of GLS for the progression of this highly lethal type of cancer. See related article by Deng et al., p. 1398pt_BR
dc.relation.ispartofCancer researchpt_BR
dc.relation.ispartofabbreviationCancer res.pt_BR
dc.publisher.cityBaltimore, MDpt_BR
dc.publisher.countryEstados Unidospt_BR
dc.publisherAmerican Association for Cancer Researchpt_BR
dc.date.issued2019-
dc.date.monthofcirculationApr.pt_BR
dc.language.isoengpt_BR
dc.description.volume79pt_BR
dc.description.issuenumber7pt_BR
dc.description.firstpage1302pt_BR
dc.description.lastpage1304pt_BR
dc.rightsFechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn0008-5472pt_BR
dc.identifier.eissn1538-7445pt_BR
dc.identifier.doi10.1158/0008-5472.CAN-19-0313pt_BR
dc.identifier.urlhttps://cancerres.aacrjournals.org/content/79/7/1302pt_BR
dc.date.available2020-05-05T20:03:51Z-
dc.date.accessioned2020-05-05T20:03:51Z-
dc.description.provenanceSubmitted by Cintia Oliveira de Moura (cintiaom@unicamp.br) on 2020-05-05T20:03:51Z No. of bitstreams: 0. Added 1 bitstream(s) on 2020-08-27T19:16:12Z : No. of bitstreams: 1 000463005700008.pdf: 170436 bytes, checksum: 1f1862c6b388a1ad3d396e32ea775f97 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-05-05T20:03:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2019en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/340186-
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.identifier.source000463005700008pt_BR
dc.creator.orcid0000-0001-9004-7176pt_BR
dc.type.formArtigopt_BR
Appears in Collections:IB - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
000463005700008.pdf166.44 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.