Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/340165
Full metadata record
DC FieldValueLanguage
dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampScariot, Pedro Paulo Menezes-
dc.contributor.authorunicampGobatto, Fúlvia de Barros Manchado-
dc.contributor.authorunicampMasselli dos Reis, Ivan Gustavo-
dc.contributor.authorunicampGobatto, Claudio Alexandre-
dc.typeArtigopt_BR
dc.titleHousing conditions modulate spontaneous physical activity, feeding behavior, aerobic running capacity and adiposity in C57BL/6J micept_BR
dc.contributor.authorMenezes Scariot, Pedro Paulo-
dc.contributor.authorManchado-Gobatto, Fulvia B.-
dc.contributor.authorProlla, Tomas A.-
dc.contributor.authorMasselli Dos Reis, Ivan G.-
dc.contributor.authorGobatto, Claudio Alexandre-
dc.subjectAtividade físicapt_BR
dc.subject.otherlanguagePhysical activitypt_BR
dc.description.abstractThere is evidence of reduced adiposity in rodents living in a large cages (LC) as compared to animals housed in small cages (SC). Because spontaneous physical activity (SPA) provides an important portion of the total daily energy expenditure, an increase of SPA in rodents kept in LC could explain their reduced body fat accumulation. The relationship between SPA and components of physical fitness (i.e. aerobic and anaerobic fitness and body leanness) has not been previously determined. We examined the effects of eight weeks of LC exposure on SPA, body composition, feeding behavior, as well as aerobic and anaerobic running capacity in adult C57BL/6J mice. Male mice were housed in cages of two different sizes for 8 weeks: a small (SC, n = 10) and large (LC n = 10) cages with 1320 cm(2) and 4800 cm(2) floor space, respectively. SPA was measured gravimetrically, and food and water intake were recorded daily. Mice had critical velocity (CV) and anaerobic running capacity (ARC) evaluated at the beginning, middle course (4th week) and at the end of study (8th week). Despite non-significant differences in each week LC-mice were more active than SC-mice by considering all SPA values obtained in the entire period of 8 weeks. The difference in SPA over the whole day was mainly due to light phase activity, but also due to activity at dark period (from 6 pm to 9 pm and from 5 am to 6 am). LC-mice also exhibited higher food and water intake over the entire 8-wk period. LC-mice had lower content of fat mass (% of the eviscerated carcass) than SC-mice (SC: 8.4 +/- 0.4 vs LC: 6.3 +/- 0.3, p < 0.05). LC-mice also exhibited reduced epididymal fat pads (% of body mass) compared to SC-mice (SC: 1.3 +/- 0.1 vs LC: 0.9 +/- 0.1, p < 0.05) and retroperitoneal fat pads (SC: 0.4 +/- 0.05 vs LC: 0.2 +/- 0.02, p < 0.05). The LC-group showed significantly higher critical velocity than SC-group at the fourth week (SC: 14.9 +/- 0.6 m.min(-1) vs LC: 18.0 +/- 0.3 m.min(-1), p < 0.05) and eighth week (SC: 17.1 +/- 0.5 m.min(-1) vs LC: 18.8 +/- 0.6 m.min(-1), p < 0.05). Our findings demonstrate that eight weeks of LC housing increases SPA of C57BL/6J mice, and this may lead to reduced fat accumulation as well as higher aerobic fitness. Importantly, our study implies that SC limits SPA, possibly generating experimental artifacts in long-term rodent studiespt_BR
dc.relation.ispartofHormones and behaviorpt_BR
dc.relation.ispartofabbreviationHorm. behav.pt_BR
dc.publisher.cityAmsterdampt_BR
dc.publisher.countryPaíses Baixospt_BR
dc.publisherElsevierpt_BR
dc.date.issued2019-
dc.date.monthofcirculationSept.pt_BR
dc.language.isoengpt_BR
dc.description.volume115pt_BR
dc.rightsFechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn0018-506Xpt_BR
dc.identifier.eissn1095-6867pt_BR
dc.identifier.doi10.1016/j.yhbeh.2019.07.004pt_BR
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0018506X18304896pt_BR
dc.description.sponsorshipCONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQpt_BR
dc.description.sponsorshipCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESpt_BR
dc.description.sponsorshipFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPpt_BR
dc.description.sponsordocumentnumber307395/2013-8; 302827/2015-3pt_BR
dc.description.sponsordocumentnumbernão tempt_BR
dc.description.sponsordocumentnumber2015/00272-6; 2015/01362-9; 2017/10201-4pt_BR
dc.date.available2020-05-05T18:14:59Z-
dc.date.accessioned2020-05-05T18:14:59Z-
dc.description.provenanceSubmitted by Mariana Aparecida Azevedo (mary1@unicamp.br) on 2020-05-05T18:14:59Z No. of bitstreams: 0. Added 1 bitstream(s) on 2020-08-27T19:17:09Z : No. of bitstreams: 1 000488889800009.pdf: 2684283 bytes, checksum: 825f711b339f1cddb6f1c4555ef02511 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-05-05T18:14:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2019en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/340165-
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.unidadeFaculdade de Ciências Aplicadaspt_BR
dc.contributor.unidadeFaculdade de Ciências Aplicadaspt_BR
dc.contributor.unidadeFaculdade de Ciências Aplicadaspt_BR
dc.contributor.unidadeFaculdade de Ciências Aplicadaspt_BR
dc.subject.keywordLocomotor behaviorpt_BR
dc.subject.keywordC57BL/6J micept_BR
dc.subject.keywordHousing conditionspt_BR
dc.subject.keywordCage sizept_BR
dc.subject.keywordSpontaneous physical activitypt_BR
dc.subject.keywordBody fatnesspt_BR
dc.subject.keywordAerobic fitnesspt_BR
dc.identifier.source000488889800009pt_BR
dc.creator.orcid0000-0003-2976-8999pt_BR
dc.creator.orcid0000-0002-1178-570Xpt_BR
dc.creator.orcid0000-0002-8025-1357pt_BR
dc.creator.orcid0000-0002-1441-7582pt_BR
dc.type.formArtigopt_BR
dc.identifier.articleid104556pt_BR
Appears in Collections:FCA - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
000488889800009.pdf2.62 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.