Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/340138
Full metadata record
DC FieldValueLanguage
dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampFerreira, Tatiane-
dc.contributor.authorunicampHuber, Stephany Cares-
dc.contributor.authorunicampMartinelli, Beatriz de Moraes-
dc.contributor.authorunicampMenezes, Fábio Hüsemann-
dc.contributor.authorunicampOrsi, Fernanda Loureiro de Andrade-
dc.contributor.authorunicampBittar, Luis Fernando-
dc.contributor.authorunicampColella, Marina Pereira-
dc.contributor.authorunicampDe Paula, Erich Vinicius-
dc.contributor.authorunicampHayakawa, Gabriela Góes Yamaguti-
dc.contributor.authorunicampMontalvão, Silmara-
dc.contributor.authorunicampAnnichino-Bizzacchi, Joyce Maria-
dc.typeArtigopt_BR
dc.titleLow prevalence of post-thrombotic syndrome in patients treated with rivaroxabanpt_BR
dc.contributor.authorFerreira, Tatiane-
dc.contributor.authorHuber, Stephany Cares-
dc.contributor.authorMartinelli, Beatriz de Moraes-
dc.contributor.authorLemos Junior, Arlindo-
dc.contributor.authorMenezes, Fabio Husemann-
dc.contributor.authorOrsi, Fernanda Andrade-
dc.contributor.authorBittar, Luis Fernando-
dc.contributor.authorGerbase de Oliveira, Luiz Frederico-
dc.contributor.authorSodre, Leonardo Ragazzi-
dc.contributor.authorMello, Tayana Teixeira-
dc.contributor.authorRielli, Glauber-
dc.contributor.authorColella, Marina Pereira-
dc.contributor.authorde Paula, Erich Vinicius-
dc.contributor.authorYamaguti-Hayakawa, Gabriela G.-
dc.contributor.authorMontalvao, Silmara-
dc.contributor.authorAnnichino-Bizzacchi, Joyce M.-
dc.subjectTromboembolismo venosopt_BR
dc.subject.otherlanguageVenous thromboembolismpt_BR
dc.description.abstractPost-thrombotic syndrome (PTS) is a complication of deep vein thrombosis (DVT). Residual vein thrombus (RVT) on Doppler Ultrasound can be associated with PTS. Limited data are available on the effect of direct oral anticoagulants (DOACs) on the long-term outcome of PTS. This study aimed to compare the prevalence of PTS and RVT, in patients with previous DVT treated with rivaroxaban or enoxaparin/warfarin. A total of 129 patients with previous proximal lower limb DVT and treated with rivaroxaban (n = 71) or enoxaparin/warfarin (n = 58) for at least 3 months were included. The Villalta scale for PTS was performed after treatment. The median duration of the DVT symptoms before anticoagulation was 7 days for both groups. The rate of PTS was 50.7% in the patients treated with rivaroxaban and 69% in the enoxaparin/warfarin group. Enoxaparin/warfarin showed an increased prevalence of PTS (P = .018). An analysis in 3 different models showed that the relative risk of PTS decreased by 76% with rivaroxaban use when compared with enoxaparin/warfarin treatment. In addition, 93 of the 129 patients were evaluated regarding the presence of RVT, of which, 11 (24.4%) and 31 (64.6%) presented with RVT for rivaroxaban and enoxaparin/warfarin, respectively (P < .0001). The RVT analysis excluded the possibility of RVT as a mediator of the association between type of treatment and PTS when comparing rivaroxaban with enoxaparin/warfarin (odds ratio (OR) = 0.14; 95% confidence interval (CI): 0.1-1.0, P = .051) with rivaroxaban compared with enoxaparin/warfarin. Rivaroxaban treatment was associated with a lower risk of PTS when compared to enoxaparin/warfarin; RVT however, was not a mediator in the association between PTS and type of treatmentpt_BR
dc.relation.ispartofVascular pharmacologypt_BR
dc.relation.ispartofabbreviationVascul. pharmacol.pt_BR
dc.publisher.cityNew York, NYpt_BR
dc.publisher.countryEstados Unidospt_BR
dc.publisherElsevierpt_BR
dc.date.issued2020-
dc.date.monthofcirculationJan.pt_BR
dc.language.isoengpt_BR
dc.description.volume124pt_BR
dc.rightsFechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn1537-1891pt_BR
dc.identifier.eissn1879-3649pt_BR
dc.identifier.doi10.1016/j.vph.2019.106608pt_BR
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S1537189119302149pt_BR
dc.description.sponsorshipFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPpt_BR
dc.description.sponsordocumentnumber2016/14172-6pt_BR
dc.date.available2020-05-05T15:34:06Z-
dc.date.accessioned2020-05-05T15:34:06Z-
dc.description.provenanceSubmitted by Mariana Aparecida Azevedo (mary1@unicamp.br) on 2020-05-05T15:34:06Z No. of bitstreams: 0. Added 1 bitstream(s) on 2020-08-27T19:17:41Z : No. of bitstreams: 1 000509004200003.pdf: 338512 bytes, checksum: 73854213788ddf75abe6977d1dd36840 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-05-05T15:34:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2019en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/340138-
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentDepartamento de Cirurgiapt_BR
dc.contributor.departmentDepartamento de Patologia Clínicapt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentDepartamento de Patologia Clínicapt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentDepartamento de Clínica Médicapt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeCentro de Hematologia e Hemoterapiapt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeCentro de Hematologia e Hemoterapiapt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.subject.keywordPost-thrombotic syndromept_BR
dc.subject.keywordRivaroxabanpt_BR
dc.subject.keywordVitamin K antagonistspt_BR
dc.subject.keywordResidual vein thrombuspt_BR
dc.identifier.source000509004200003pt_BR
dc.creator.orcid0000-0003-0266-4495pt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcid0000-0002-7908-9073pt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcid0000-0003-1539-7912pt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcidsem informaçãopt_BR
dc.type.formArtigopt_BR
dc.identifier.articleid106608pt_BR
Appears in Collections:FCM - Artigos e Outros Documentos
HEMO - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
000509004200003.pdf330.58 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.