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Type: Artigo
Title: Intranodal angiomyomatous hamartoma in a cynomolgus monkey
Author: Thirion-Delalande, Catherine
Gervais, Frederic
Palate, Bernard
Forster, Roy
Schenka, Andre Almeida
Abstract: We describe here an angiomyomatous hamartoma in the right axillary lymph node of a three-year-old male cynomolgus monkey (Macaca fascicularis), used as a control subject in a short-term toxicity study. This is a very rare lesion that has been reported almost exclusively in inguinal lymph nodes, and to date only in human beings. In the present case, light microscopy revealed partial replacement of the lymph node parenchyma by a disorganized, irregular vascular network, sparsely distributed smooth muscle cells, and a fibro-adipocytic stroma. This was considered to be fortuitous given the age of the animal, with no clinical or toxicological significance. To the best of our knowledge, this is the first report of an intranodal angiomyomatous hamartoma in a nonhuman animal species.
Subject: Hamartoma
Country: Estados Unidos
Editor: Sage
Rights: Fechado
Identifier DOI: 10.1177/0192623318814711
Date Issue: 2019
Appears in Collections:FCM - Artigos e Outros Documentos

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