Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/337629
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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampLuiz, Livia Cocato-
dc.contributor.authorunicampMarson, Fernando Augusto de Lima-
dc.contributor.authorunicampAlmeida, Celize Cruz Bresciani-
dc.contributor.authorunicampToro, Adyléia Aparecida Dalbo Contrera-
dc.contributor.authorunicampNucci, Anamarli-
dc.contributor.authorunicampRibeiro, José Dirceu-
dc.typeArtigopt_BR
dc.titleAnalysis of motor and respiratory function in Duchenne muscular dystrophy patientspt_BR
dc.contributor.authorLuiz, Livia Cocato-
dc.contributor.authorLima Marson, Fernando Augusto-
dc.contributor.authorBresciani Almeida, Celize Cruz-
dc.contributor.authorDalbo Contrera Toro, Adyleia Aparecida-
dc.contributor.authorNucci, Anamarli-
dc.contributor.authorRibeiro, Jose Dirceu-
dc.subjectDistrofia muscular de Duchennept_BR
dc.subjectTestes de função respiratóriapt_BR
dc.subject.otherlanguageMuscular Dystrophy, Duchennept_BR
dc.subject.otherlanguageRespiratory function testspt_BR
dc.description.abstractDuchenne muscular dystrophy(DMD) shows motor and respiratory impairment. Methods: 19 DMD patients (DMDG) (nine ambulatory and 10 non-ambulatory) were evaluated through motor function measure (MFM), 6-minute walk test (6MWT), respiratory muscle strength, cough peak flow, spirometry and volumetric capnography (VCap) tools. Control group that performed spirometry and VCap (CG1-n = 17) were different from those that performed the 6MWT (CG2-n = 8). Results: The follow tools were assessed (p < 0.05): (i) MFM: Ambulatory patients showed higher values than non-ambulatory patients; (ii) 6MWT: DMDG walked a shorter distance and showed higher respiratory rate at rest and heart rate (HR) at rest than CG2; (iii) Spirometry: DMDG and non-ambulatory patients had minor values achieved in spirometry when compared with CG1 and ambulatory patients, respectively; (iv) VCap: DMDG when compared with CG1 showed: (< 11 years-old) lower values in VCap parameters; (> 11 years-old): higher HR and lower slope 2. There was correlation between spirometry, mainly for zFEV(1)/FVC, and MFM. Conclusion DMDG showed motor (MFM/6MWT) and respiratory (spirometry/VCap) deterioration when compared with CG. Non-ambulatory condition was associated with worse MFM and spirometry.pt_BR
dc.relation.ispartofRespiratory physiology & neurobiologypt_BR
dc.relation.ispartofabbreviationRespir. physiol. neurobiol.pt_BR
dc.publisher.cityAmsterdampt_BR
dc.publisher.countryHolandapt_BR
dc.publisherElsevierpt_BR
dc.date.issued2019-
dc.date.monthofcirculationApr.pt_BR
dc.language.isoengpt_BR
dc.description.volume262pt_BR
dc.description.firstpage1pt_BR
dc.description.lastpage11pt_BR
dc.rightsFechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn1569-9048pt_BR
dc.identifier.eissn1878-1519pt_BR
dc.identifier.doi10.1016/j.resp.2019.01.009pt_BR
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S1569904818301204pt_BR
dc.description.sponsorshipFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPpt_BR
dc.description.sponsordocumentnumber2011/12939-4; 2015/12183-8; 2015/12858-5; 0648/2015; 2011/18845-1pt_BR
dc.date.available2020-03-27T13:41:01Z-
dc.date.accessioned2020-03-27T13:41:01Z-
dc.description.provenanceSubmitted by Bruna Maria Campos da Cunha (bcampos@unicamp.br) on 2020-03-27T13:41:01Z No. of bitstreams: 0. Added 1 bitstream(s) on 2020-07-20T14:17:25Z : No. of bitstreams: 1 000464487300001.pdf: 686436 bytes, checksum: 29e9becdf55cc0768a70b91cbdf1b021 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-03-27T13:41:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2019en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/337629-
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentDepartamento de Pediatriapt_BR
dc.contributor.departmentDepartamento de Neurologiapt_BR
dc.contributor.departmentDepartamento de Pediatriapt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.subject.keywordGenetic diseasept_BR
dc.subject.keywordLung functionpt_BR
dc.subject.keywordMotor skillspt_BR
dc.subject.keywordMuscular dystrophypt_BR
dc.subject.keywordSpirometrypt_BR
dc.identifier.source000464487300001pt_BR
dc.creator.orcidSem informaçãopt_BR
dc.creator.orcidorcid.org/0000-0003-4955-4234pt_BR
dc.creator.orcidSem informaçãopt_BR
dc.creator.orcidorcid.org/0000-0001-5777-1146pt_BR
dc.creator.orcidSem informaçãopt_BR
dc.creator.orcidorcid.org/0000-0002-3387-5642pt_BR
dc.type.formArtigopt_BR
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