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Type: Artigo
Title: Enzymatic treatment improves the antioxidant and antiproliferative activities of adenanthera pavonina l. seeds
Author: Peixoto Araujo, Nayara Macedo
Pereira, Gustavo Araujo
Arruda, Henrique Silvano
Prado, Livia Garcia
Tasca Gois Ruiz, Ana Lucia
Eberlin, Marcos Nogueira
Soares de Castro, Ruann Janser
Pastore, Glaucia Maria
Abstract: We evaluated the effect of enzymatic treatment by amylase, cellulase and protease on antioxidant and antiproliferative activities of Adenanthera pavonina L. seeds. The effect was evaluated by using an experimental mixture design. The results showed that the antioxidant activity of the seeds increased after the enzymatic treatment. The enzymatic treatment using protease and cellulase (1:1, v/v) showed the highest values of antioxidant activity due to the increase of phenolic compounds content, mainly phenolic acids. The antiproliferative activity of the extract obtained by optimum enzymatic treatment was evaluated. We found the antiproliferative activity against the tumour lineage of prostate (PC-3) and kidney (786-0) was improved after enzymatic treatment. This work provides information that may be useful in handling of functional foods and/or drugs, since the functional properties of seeds such as antioxidant and antitumor activities were improved by enzymatic treatment with protease and cellulase
Subject: Atividade antitumoral
Compostos bioativos
Country: Países Baixos
Editor: Elsevier
Rights: Fechado
Identifier DOI: 10.1016/j.bcab.2019.01.040
Date Issue: 2019
Appears in Collections:FEA - Artigos e Outros Documentos

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