Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/337399
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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampSoares, Marco César Prado-
dc.contributor.authorunicampVit, Franciele Flores-
dc.contributor.authorunicampSuzuki, Carlos Kenichi-
dc.contributor.authorunicampTorre, Lucimara Gaziola de la-
dc.contributor.authorunicampFujiwara, Eric-
dc.typeArtigopt_BR
dc.titlePerfusion microfermentor integrated into a fiber optic quasi-elastic light scattering sensor for fast screening of microbial growth parameterspt_BR
dc.contributor.authorSoares, Marco César Prado-
dc.contributor.authorFlores, Franciele-
dc.contributor.authorSuzuki, Carlos Kenichi-
dc.contributor.authorGaziola de la Torre, Lucimara-
dc.contributor.authorFujiwara, Eric-
dc.subjectCrescimento celularpt_BR
dc.subjectTecnologia de fibra ópticapt_BR
dc.subject.otherlanguageFiber optic technologypt_BR
dc.subject.otherlanguageCell enlargementpt_BR
dc.description.abstractThis research presents a microfermentor integrated into an optical fiber sensor based on quasi-elastic light scattering (QELS) to monitor and swiftly identify cellular growth kinetic parameters. The system uses a 1310 nm laser light that is guided through single-mode silica optical fibers to the interior of perfusion chambers, which are separated by polycarbonate membranes (470 nm pores) from microchannels, where a culture medium flows in a constant concentration. The system contains four layers, a superior and an inferior layer made of glass, and two intermediate poly(dimethylsiloxane) layers that contain the microchannels and the perfusion chambers, forming a reversible microfluidic device that requires only the sealing of the fibers to the inferior glass cover. The QELS autocorrelation decay rates of the optical signals were correlated to the cells counting in a microscope, and the application of this microsystem to the monitoring of alcoholic fermentation of Saccharomyces cerevisiae resulted in the kinetic parameters of KM = 4.1 g/L and μm = 0.49 h−1. These results agree with both the data reported in the literature and with the control batch test, showing that it is a reliable and efficient biological monitoring system.pt_BR
dc.relation.ispartofSensorspt_BR
dc.relation.ispartofabbreviationSensorspt_BR
dc.publisher.cityBaselpt_BR
dc.publisher.countrySuíçapt_BR
dc.publisherMDPIpt_BR
dc.date.issued2019-
dc.date.monthofcirculationMaypt_BR
dc.language.isoengpt_BR
dc.description.volume19pt_BR
dc.description.issuenumber11pt_BR
dc.rightsAbertopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn1424-8239pt_BR
dc.identifier.eissn1424-8220pt_BR
dc.identifier.doi10.3390/s19112493pt_BR
dc.identifier.urlhttps://www.mdpi.com/1424-8220/19/11/2493/htmpt_BR
dc.description.sponsorshipCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESpt_BR
dc.description.sponsorshipFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPpt_BR
dc.description.sponsordocumentnumberSem informaçãopt_BR
dc.description.sponsordocumentnumber2017/20445-8pt_BR
dc.date.available2020-03-25T17:30:34Z-
dc.date.accessioned2020-03-25T17:30:34Z-
dc.description.provenanceSubmitted by Bruna Maria Campos da Cunha (bcampos@unicamp.br) on 2020-03-25T17:30:34Z No. of bitstreams: 1 000472133300071.pdf: 3854050 bytes, checksum: 0c859fab0eaa251b04e2d2f56447eaea (MD5)en
dc.description.provenanceMade available in DSpace on 2020-03-25T17:30:34Z (GMT). No. of bitstreams: 1 000472133300071.pdf: 3854050 bytes, checksum: 0c859fab0eaa251b04e2d2f56447eaea (MD5) Previous issue date: 2019en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/337399-
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentDepartamento de Engenharia de Manufatura e Materiaispt_BR
dc.contributor.departmentDepartamento de Engenharia de Materiais e Bioprocessospt_BR
dc.contributor.departmentDepartamento de Sistemas Integradospt_BR
dc.contributor.unidadeFaculdade de Engenharia Mecânicapt_BR
dc.contributor.unidadeFaculdade de Engenharia Químicapt_BR
dc.subject.keywordFiber optic sensorpt_BR
dc.subject.keywordMicrofermentorpt_BR
dc.subject.keywordQuasi-elastic light scatteringpt_BR
dc.subject.keywordMicrobial growth screeningpt_BR
dc.subject.keywordBiological monitoringpt_BR
dc.identifier.source472133300071pt_BR
dc.creator.orcid0000-0002-5219-5124pt_BR
dc.creator.orcid0000-0002-0047-8384pt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcid0000-0002-8179-1160pt_BR
dc.creator.orcid0000-0001-8169-9738pt_BR
dc.type.formArtigopt_BR
dc.identifier.articleid2493pt_BR
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