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Type: Artigo
Title: Characterization and in vitro evaluation of chitosan/konjac glucomannan bilayer film as a wound dressing
Author: Gomes Neto, Reginaldo Jose
Genevro, Giovana Maria
Paulo, Leticia de Almeida
Lopes, Patricia Santos
de Moraes, Mariana Agostini
Beppu, Marisa Masumi
Abstract: A novel bilayer film of chitosan and konjac glucomannan were prepared by the two-step casting technique. Blend films were also prepared to investigate the interactions between the two polymers in the interfacial region of the bilayer structure. Scanning electron microscopy, Fourier transform infrared spectroscopy, and X-ray diffraction analysis showed that, unlike in the blends, the physicochemical properties of each biopolymer were preserved in the bilayer film. Differential scanning calorimetry and thermogravimetric analysis also indicated a good thermostability and miscibility for both polymers, probably due to strong hydrogen bonds between their polymer chains. Biological, mechanical and water vapor transmission tests showed a high biocompatibility, low cytotoxicity, and suitable mechanical and barrier properties of the bilayer films for wound dressing applications
Subject: Biopolímeros
Country: Reino Unido
Editor: Elsevier
Rights: Fechado
Identifier DOI: 10.1016/j.carbpol.2019.02.017
Date Issue: 2019
Appears in Collections:FEQ - Artigos e Outros Documentos

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