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|Title:||Laryngeal Epstein-Barr virus-associated smooth muscle tumor in an undernourished child|
|Author:||Soares, Ciro Dantas|
Diaz Molina, Juan Pablo
de Lima Morais, Thayna Melo
de Almeida, Oslei Paes
de Lima Morais, T.M.
de Almeida, O.P.
|Abstract:||Smooth muscle tumors associated with Epstein–Barr virus infections (EBV–SMT) of laryngeal origin are exceedingly rare and have been reported in few adult patients, but not in children. This reported case describes a lesion found in the larynx of an 8-year-old Guatemalan undernourished girl. Microscopically, the lesion showed a highly cellular mesenchymal spindle cell tumor, containing frequent lymphocytes. The immunohistochemical analysis revealed positivity for α-smooth muscle actin and h-caldesmon. In addition, most of the tumor cells were positive for EBV by in situ hybridization. To the best of the author’s knowledge, this is the first literature-reported case of laryngeal EBV–SMT occurring in an undernourished child|
|Subject:||Infecções por vírus Epstein-Barr|
|Appears in Collections:||FOP - Artigos e Outros Documentos|
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