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Type: Artigo
Title: Laryngeal Epstein-Barr virus-associated smooth muscle tumor in an undernourished child
Author: Soares, Ciro Dantas
Carlos, Roman
Diaz Molina, Juan Pablo
de Lima Morais, Thayna Melo
de Almeida, Oslei Paes
Soares, C.D.
Carlos, R.
Molina, J.P.D.
de Lima Morais, T.M.
de Almeida, O.P.
Abstract: Smooth muscle tumors associated with Epstein–Barr virus infections (EBV–SMT) of laryngeal origin are exceedingly rare and have been reported in few adult patients, but not in children. This reported case describes a lesion found in the larynx of an 8-year-old Guatemalan undernourished girl. Microscopically, the lesion showed a highly cellular mesenchymal spindle cell tumor, containing frequent lymphocytes. The immunohistochemical analysis revealed positivity for α-smooth muscle actin and h-caldesmon. In addition, most of the tumor cells were positive for EBV by in situ hybridization. To the best of the author’s knowledge, this is the first literature-reported case of laryngeal EBV–SMT occurring in an undernourished child
Subject: Infecções por vírus Epstein-Barr
Country: Alemanha
Editor: Springer
Rights: Fechado
Identifier DOI: 10.1007/s12105-018-0960-0
Date Issue: 2019
Appears in Collections:FOP - Artigos e Outros Documentos

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