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Type: Outro documento
Title: Laryngeal Epstein-Barr virus-associated smooth muscle tumor in an undernourished child
Author: Soares, Ciro Dantas
Carlos, Roman
Diaz Molina, Juan Pablo
de Lima Morais, Thayna Melo
de Almeida, Oslei Paes
Abstract: Smooth muscle tumors associated with Epstein-Barr virus infections (EBV-SMT) of laryngeal origin are exceedingly rare and have been reported in few adult patients, but not in children. This reported case describes a lesion found in the larynx of an 8-year-old Guatemalan undernourished girl. Microscopically, the lesion showed a highly cellular mesenchymal spindle cell tumor, containing frequent lymphocytes. The immunohistochemical analysis revealed positivity for alpha-smooth muscle actin and h-caldesmon. In addition, most of the tumor cells were positive for EBV by in situ hybridization. To the best of the author's knowledge, this is the first literature-reported case of laryngeal EBV-SMT occurring in an undernourished child
Subject: Câncer em crianças
Herpesvirus humano 4
Country: Alemanha
Editor: Springer
Rights: Fechado
Identifier DOI: 10.1007/s12105-018-0960-0
Date Issue: 2019
Appears in Collections:FOP - Artigos e Outros Documentos

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