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|Title:||Laryngeal Epstein-Barr virus-associated smooth muscle tumor in an undernourished child|
|Author:||Soares, Ciro Dantas|
Diaz Molina, Juan Pablo
de Lima Morais, Thayna Melo
de Almeida, Oslei Paes
|Abstract:||Smooth muscle tumors associated with Epstein-Barr virus infections (EBV-SMT) of laryngeal origin are exceedingly rare and have been reported in few adult patients, but not in children. This reported case describes a lesion found in the larynx of an 8-year-old Guatemalan undernourished girl. Microscopically, the lesion showed a highly cellular mesenchymal spindle cell tumor, containing frequent lymphocytes. The immunohistochemical analysis revealed positivity for alpha-smooth muscle actin and h-caldesmon. In addition, most of the tumor cells were positive for EBV by in situ hybridization. To the best of the author's knowledge, this is the first literature-reported case of laryngeal EBV-SMT occurring in an undernourished child|
|Subject:||Câncer em crianças|
Herpesvirus humano 4
|Appears in Collections:||FOP - Artigos e Outros Documentos|
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